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Histopathology 6th Ed. Robertson F. Ogilvie M.D. D.Sc. xi + 514 pages 400 photomicrographs (color) E. & S. Livingston Ltd. and The Williams & Wilkins Co. Baltimore $14.50 1962

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HISTOPATHOLOGY, 6th Ed., Robertson
F. Ogilvie, M.D., D.Sc., xi 514 pages,
400 photomicrographs (color), E. & S .
Livingston, Ltd., and The Williams &
Wilkins Co., Baltimore, $14.50, 1962.
described in numerous organs. The characteristics of the granulomatous inflammations are well covered. Two chapters are
devoted to tumors. The first describes the
benign tumors - lipoma, myxoma, leiomyThis is the sixth edition of “Histopathol- oma, chordoma, ostemoa, hemangioma,
ogy.” The first edition, which appeared lymphanigioma, adenoma. There are four
in 1940, was based on a series of lectures pages of descriptive text and five colored
in pathologic histology delivered at Edin- micrographs on haemangiomas, which
burgh University. Thirty pages of text seems disproportionally large in compariand 66 colored micrographs have been son to the relative importance of these
added to the fifth edition and the present tumors. Near the end of this chapter is
volume contains 400 colored micrographs described some of the nervous system
and 512 pages. This book is intended to tumors, including the glioblastoma multibe a companion to a standard textbook forme, neuroblastoma, neurinoma, ganof pathology. Dr. Ogilvie has designed glioneuroma, and the chromaffin parathis volume to meet the need of the histol- ganglioma. Potassium bichromate and
ogist as well as the graduate seeking more giemsa stains graphically illustrate the
specialized knowledge in pathologic his- latter tumor. The second chapter of the
tumors, dealing primarily with maligAnatomists too often fail to acknowl- nancies, opens with a discussion of the
edge that there is a spectrum of normal spindle-cell sarcoma. In keeping with its
just as there is a spectrum of pathological. importance the malignant melanoma has
Histologists, in particular, should be able ample text devoted to it. Among the
to appreciate the extent to which tissue carcinomas, discussions of the stomach,
alterations can occur before the process bronchus, testis, and tongue are prebecomes pathological. It is, therefore, as sented. A useful feature of this section is
important for a histologist to have a basic the illustration of H & E sections of pleufoundation in pathology as it is for a ral fluid from patients with carcinoma of
pathologist to know histology. This vol- the bronchus, thereby permitting correlaume has been designed to give such a tion with the histopathology of the tumor.
basis for the microscopic recognition of Chapters seven and eight are devoted to
tissue changes.
the circulatory system. Nine pages of disThe scope of the book covers the com- cussion are presented on arterial atheromon diseases in Great Britain. The mata, endarteritis, and medial calcificavolume is presented in 18 chapters. A tion. The colored illustrations of elastic
short macroscopic description precedes the tissue and van Gieson stains accentuate
microscopic description of each disease the usefulness of this section. Although
process. The first chapter describes the temporal arteritis (giant cell arteritis) is
disturbances of nutrition, namely basic rare, the author has devoted three pages
pathological changes (Zenker’s hyaline of text to its description. The specific
degeneration, cloudy swelling, fatty degen- criteria for making a diagnosis of maligeration, etc.). The colored micrographs nant hypertension differ in Great Britain
are advantageous since they truly illus- and the United States. Chapter nine, the
trate the staining reactions of the histo- respiratory system, covers pneumonia and
chemical methods (fat, mucin stains) tuberculosis quite well but lacks any disused to demonstrate these entities. In- cussion of the common, and sometimes
flammation and repair and specific in- fatal asthma. The alimentary system is
flammations cover two chapters. Acute covered in two sections: the mouth, stominflammation (characterizing the cell type ach and intestines are in the first section,
present) and chronic inflammation are and the liver, gall bladder, and pancreas
in the second. The discussion of the
gastric ulcer emphasizes the four zones
of tissue change necessary for making
this diagnosis. Regional ileitis is well
covered however, there is a lack of description of the equally nonspecific ulcerative
colitis. The section on the liver is concise and well illustrated. The urinary
system is considered incomplete since it
lacks any illustration or discussion of the
histopathology and pathogenesis of chronic
pyelonephritis. The chapter on the haematopoietic system opens with the discussion
of hematopoiesis and a folded chart depicting the monophyletic theory of cell
development. The illustrations in this
chapter are not considered to be as good
as those in text books of hematology, although May Grunwald - Giemsa stains
were used. There is also included a discussion of acute splenitis (acute splenic
tumor, acute splenic enlargement). The
text on the nervous system is limited, but
the lesions are well illustrated with special stains, such as Weigert and van Gieson. There is a three page discussion of
von Economo’s disease (epidemic encephalitis) although there has not been a
reported case of this entity in the United
States since 1929. The chapter on skin
lacks any discussion of pemphigus, probably the only primary skin disease with
an invariably fatal outcome; yet there are
two pages devoted to the pilonidal sinus.
The succinct presentation of the locomotor
system has a discussion of osteomyelitis,
rickets, osteitis deformans, osteogenesis
imperfecta, and rheumatoid arthritis. Trichinosis and ganglion are also described.
The last chapter on endocrine lesions
covers entities such as exophthalmic
goitre, myxedema, the pituitary adenomas,
and Addison’s disease.
The most notable feature of the book
is the 400 colored micrographs. The quality of the reproductions is good and the
magnifications are effective enough to
characterize the tissue changes. The only
deficiency in the quality of illustration is
in the first chapter. The colored micrographs in this chapter are old, having been
carried over from previous editions, and
therefore, are not as good as those obtainable today. Nevertheless, the colored
plates, made from Finlay colored transparencies by Mr. T. C. Dodds, convey a
more realistic impression of the stained
section. The index is complete. There
has been substantial increase in the price
of the book since the fifth edition.
Because of the scope of the volume and
the price, the book is more valuable to
the graduate student and histologist interested in pathology than it is to the
medical student. Many medical students,
however, would find this book a useful
supplement to the standard pathology
texts. Also, ins this respect the volume fulfills a genuine need.
Department of Pathology
LSU School of Medicine
Bourne. vii i168 pages, 59 figures.
$3.00. Bailliere, Tindall and Cox, London, and Williams and Wilkins Company, Baltimore. Seventh edition. 1960.
G. A. Kerkut. x f 174 pages, 43 figures.
$5.00. Pergamon Press, New York.
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400, livingstone, histopathology, color, 514, 1962, page, ltd, wilkins, william, photomicrographic, robertson, 6th, baltimore, ogilvie
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