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2002
biochemical syntheses, microbiological syntheses
biochemical syntheses, microbiological syntheses
O 0035
Active Site Mapping of Porcine Liver Esterase (PLE) and Porcine
05 - 028 Pancreatic Lipase (PPL): Stereo and Regiochemical Outcome of
Hydrolysis of Conformationally Constrained Esters.
— Compounds
(I) and (IV) are prepared as model compounds for the study of the regio- and
stereoselectivity of the porcine liver esterase (PLE) and porcine pancreatic
lipase (PPL) catalyzed hydrolysis. Results support the Jones’ model for
PLE and provide new insights regarding the active site model for PPL. —
(BASAK, AMIT; RUDRA, KAKALI RANI; GHOSH, SUBHASH CHANDRA;
BHATTACHARYA, GAUTAM; Indian J. Chem., Sect. B: Org. Chem. Incl.
Med. Chem. 40 (2001) 10, 974-980; Dep. Chem., Indian Inst. Technol.,
Kharagpur 721 302, India; EN)
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