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BOOK REVIEWS
senior clinical students, as it does not provide an account of
general pathology. The spirit of the new core curriculum is
evident but I am surprised to hear that the authors were
allowed to teach pathology, as it seems that teaching and
-ologies are banned and we should now be facilitating student
enquiry into abnormal structure!
D. T. M?M????
Royal Group of Hospitals Trust and
The Queen?s University of Belfast
Contemporary Issues in Surgical Pathology. Pathology of
Lymph Nodes.
L??????? M. W???? (Ed.). Churchill Livingstone, Edinburgh,
1996. No. of pages: 453. Price: �.00.
In the preface to this volume of Contemporary Issues in
Surgical Pathology, Lawrence Weiss makes it clear that this is
not intended as a comprehensive text on haematopathology.
Instead, the book aims at providing an in-depth coverage of a
limited number of important topics. In practice, the 17 authors
cover a wide range of topics in 11 chapters. There is an opening
chapter, giving an up-to-date account of molecular haematopathology with details of the techniques used, followed by
findings in all the major categories of lymphoma. There follow
excellent and authoritative chapters on reactive lymphadenopathies and separate chapters on classical Hodgkin?s disease
and nodular lymphocyte predominant Hodgkin?s disease.
While the importance of classic Reed?Sternberg cells in defining and classifying Hodgkin?s disease is not disputed in the era
before immunohistochemistry came into widespread use, it is
refreshing to read the statement by the authors of the chapter
on classical Hodgkin?s disease: ?We believe that a diagnosis of
Hodgkin?s disease may be rendered on the basis of Reed?
Sternberg variants, even in the absence of classical RS cells
. . .?. A few years ago, that statement would have earned the
authors a fatwa.
There is a brief chapter on the classification of nonHodgkin?s lymphoma that includes discussion of the REAL
classification. The need for this is apparent, with a number of
the chapters suffering from the obfuscation of Working Formulation terminology. The remaining chapters include an
excellent account of low-grade B-cell lymphomas and a chapter on diffuse, aggressive non-Hodgkin?s lymphomas. The
chapter on peripheral cell lymphomas contains a large amount
of data but does little to clarify this complex group of
lymphomas. There is a valuable chapter on post-transplant
lymphoproliferation disorders, a chapter of Ki-1 positive
large cell lymphomas (anaplastic large cell lymphoma), and a
final, interesting chapter on histiocytic and dendritic cell
proliferations.
The illustrations in this book are in black and white and
most are of a high standard. The chapters are well referenced,
up to 1995, making this a valuable source book for the next
few years. Haematopathologists will undoubtedly find this
volume of interest. If, however, you are looking for a diagnostic text, buy the AFIP Fascicle.
D. H. W?????
School of Medicine
Southampton University Hospitals Trust
Cells, Tissues and Diseases. Principles of General Pathology.
G. M???? and I??????? J????. Blackwell Science, Oxford,
1996. No. of pages: 974.
Somewhat irrationally, I am impressed by big books and this
one weighed in at a satisfactory 2� kg, measured
? 1997 John Wiley & Sons, Ltd.
247
278#215#47 mm, and has 974 pages bearing 1074 illustrations. I quite liked the cover?obviously a picture of an
endothelium en face with adherent lipid droplets. So far, so
good and then I opened the book and found a detailed
explanation of the cover illustration?it is a pun on the title of
the book. My heart sank. A pun which required a detailed
explanation seems barely worth the effort. My spirits were
restored, however, on reading the preface, which contained a
robust defence of the science of general pathology. I gleefully
noted (for future use in my department) the statement??As
regards the bacteriologists and immunologists, their specialities were taught as part of pathology only a few decades ago.
When they branched off, they also sawed themselves off from
the main trunk and dropped all connections with the study of
disease.?
The authors are not modest in the scope of the clientele
which they hope will be attracted to their book??all pathologists, as well as physicians, all teachers of pathology, pathology residents, inquisitive medical students, biologists,
including college teachers, molecular biologists, immunologists, bacteriologists, physiologists, researchers, graduate
students and basic scientists?! There is nothing wrong with
ambition, but the reality is that not all these groups will rush
out to buy this book.
In the preface the authors pose a fundamental
question??Why another General Pathology textbook?? Why,
indeed, and I am not sure that the authors give an entirely
convincing answer. Their ambition is to produce a book
suitable for medical and non-medical readers and which would
(i) focus on the cell as the ?elementary patient?, (ii) emphasize
principles, (iii) use the historical approach, (iv) use illustrations
integral to the message, (v) emphasize that the manifestations
of disease can be found in all walks of life, (vi) tell a single
story from beginning to end, and (vii) try to cope constructively with the literature explosion. There are, of course, a
number of distinguished textbooks currently available which
could lay claim to any or most of these attributes. I like the
historical approach, but it is not to everyone?s taste. I also
enjoy illustrations which are integral to the message and the
new line drawings in the book are generally excellent. The
quality of some of the other illustrations, however, is quite
variable?it is very difficult, for example, to interpret Figure
1.2 and the publishers need to pay attention to the black and
white pictures throughout.
The book has five main subdivisions?Cellular Pathology,
Injury and Inflammation, Vascular Disturbances, Immunopathology, and Tumours. All are well written and informative
and I would single out Injury and Inflammation and Vascular
Disturbances as being truly excellent. In terms of the potential
readership, the book is likely to be of most benefit to those
without formal medical training who have a particular need
and desire to obtain an intellectual framework in general
pathology.
We are informed that the book is the product of conjugal
enterprise and, as such, is of ?single authorship?. It seems that
the enterprise was herculean in scope and consumed a large
quantity of cellulose. One is reassured to be told that 101 trees
have been planted in compensation. The end result is a literary
style which is certainly individualistic. I found it very readable?
others may not. Books with a single or a limited number of
authors are sometimes accused of lack of balance. Looking at
the section on pathological calcification (a topic often dealt
with in a superficial naive fashion), I found the treatment to be
reassuringly quite sophisticated. Overall, the book evidences a
welcome integrating approach. One of the most telling illustrations is the first (Figure P-1). This shows the eight levels
(genes]populations) at which diseases may be studied. Nowadays we are so focused at genetic and molecular level that it
??????? ?? ?????????, ???. 183: 242?248 (1997)
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