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Annual review of neuroscience vol6 Edited by W. Maxwell Cowan Eric M. Shooter Charles F. Stevens and Richard F

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BOOKS
Reviews
Orthopaedic Management of Neuromuscular Disorders
By James C . Drenizan
Philadelphia,J . B. Lippincott Company, 1983
306 pp, illustrated, $42.00
Frequently our expertise in the diagnosis of neuromuscular
disorders exceeds our appreciation of treatment options. Potentially beneficial orthopedic procedures are particularly
difficult for neurologists to assess. Drennan’s book attempts
to bridge the gap between neurologist and orthopedic surgeon, but falls short. One would like to see more clearly
delineated the surgical options available for various
neuromuscular problems, their indications, and nonsurgical
alternatives, risks, and expected benefits. The orthopedic
surgery in this book is basically sound, but the information is
presented in a way few neurologists would find useful. Collaboration with a neurologist in a subsequent edition would
broaden the book’s appeal and make it more attractive to its
intended audience.
Kenneth H . Fischbeck, M D
Philadelphia. PA
Children w i t h Brain Dysfunction:
Neurology, Cognition, Language, and Behavior
(The International Review of Child Neurology)
By Isabelle Rapin, M D
New York, Raoen Press, I982
30 1 pp , illustrated
This book is a well-written orientation to what is known in
the field. The references are complete and up-to-date, as is
the classification of the dysphasic syndromes and epilepsies.
The illustrations and their legends are exceedingly well done,
as are the sections on language and the neuropsychological
testing battery. It is unclear to whom the text is aimed. The
glossary appears oriented to the nonphysician. Many important sections, such as those on cerebral palsy, seizures, and
neurotransmitters, are too simplified for the neurologist,
whereas many of the figures and legends, such as those on
variations in the neocortex, are too detailed for the nonneurologist. The monograph is perhaps most suitable for the
adult neurologist who wishes an overall view of the subject.
John J . Caronna. M D
New York, NY
Psychiatric Aspects of Neurologic Disease,
Second edition
Seminars in Psychiatry, Vol 2
Edited by D. Frank Benson and D. Blumer
New York, Grune and Stratton, 1982
444 pp, illustrated
This book is a second edition of a monograph published
under the same title in 1975. Its appearance reflects what the
editors regard as “a considerable increase in interest and activity . . . in the borderland between psychiatry and neurology.” Chapters cover a variety of behavioral disturbances
5 10
including confusional states, psychiatric manifestations of
epilepsy, episodic dyscontrol, dementias, chronic pain, tardive dyskinesia, brain trauma, amnesia, multiple sclerosis,
and stuttering. The text tends to be empirical rather than
pathophysiological in its approach and, from the standpoint
of the neurologist, exhibits considerable unevenness. For example, one chapter describes “cortical” dementias, meaning
Alzheimer’s and Pick’s disease; however, no area of the book
defines satisfactorily what conditions might be considered
subcortical dementias and why, nor is any serious attention
given to references since 1977 o n subcortical cholinergic
mechanisms in Alzheimer’s disease. Considerations such as
the dementia of Huntington’s disease are omitted altogether.
References in a few chapters date to as late as 1981,but these
are the exception. Considerable discussion is devoted to empirical concepts, unanchored by considerations of underlying
mechanisms of anatomy, physiology, or metabolism. Even
the editor criticizes the chapter entitled “The Treatable Dementias,” stating in a commentary that “the broad picture
expressed . . . goes well beyond the ability of current data to
support its suggestion that most dementia is treatable.” Remarkably, no chapter definitively discusses the important and
often very difficult problem of differentiating between depression and dementia, alone or in combination. Similarly,
essentially nothing is mentioned about the risk of druginduced toxic deliria as a form of pseudodementia in the
elderly. The index contains no reference to Huntington’s
disease, and delirium is mentioned only in its restricted form
of delirium tremens.
Fred Pbm, M D
New Youk, N Y
Annual Review of Neuroscience, V o l 6
Edited by W. Maxwell Cowan, Eric M . Shooter,
Charles F. Stevens, and Richard F . Thompson
Palo Alto, CA, Annual Reviews Inc, 1983
563 PP
The extraordinarily rapid development of new scientific discoveries leading to new concepts about che neurobiology of
the nervous system and muscular system makes this Annual
Review series indispensable to the intellectually curious
neuroscientist of either clinical or fundamental disposition.
This volume contains almost uniformly strong and informative review chapters covering, respectively, dopamine receptors, functional anatomy of basal ganglia, thalamocortical
auditory systems, receptor sensitivity modification, microcircuitry of the retina and visual cortex, hair cell transduction in the acoustic system, positron emission tomography,
anatomic integration of the hypothalamus, plasticity of
somatosensory cortex following peripheral nerve damage,
neurosecretory activity in hypothalamus, spinal mechanisms
of nociception, neuronal ion transport proteins, cellular processes of learning, protein phosphorylation and neural function, and molecular approaches to the nervous system.
A useful addendum to the actual reviews in this volume is a
list of neurobiology reviews that have appeared in other disciplinary volumes of the Annual Review series during 1982.
Fved Plum, M D
N w York, N Y
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