Atlas of human cross-sectional Anatomy. By Donald R. Cahill and Matthew J. Orland Philadelphia Lea & Febiger 1984 139 pp illustrated $29код для вставкиСкачать
Review Handbook of Neurochernistry Edited by Abel Lajtha New York, Plenum Press Vol5, “MetabolicTurnozler in the Nervous System.” 495; pp, 1983 Vol6, “Receptors in the Nervous System,” 668 pi?, I984 Volume 5 contains 2 1 chapters contributed by authors from the United States, Canada, and Europe. In general the individual chapters are carefully edited, well written, and interesting, and they provide useful information. However, the title of Volume 5 is unfortunate and the chapters are not organized in a logical sequence. Volume 3 in the series is entitled “Metabolism in the Nervous System.” The similarity of the titles is confusing. Surely “metabolism” implies turnover. Apparently “metabolic turnover” in Volume 5 is meant to include protein translocation ( e g , retrograde and anterograde axonal transport) and uptake processes for hexoses, amino acids, and other small molecules. Volume 5 contains chapters on brain proteins (S-100, tubulin, nerve growth factor) in which there is little if any description of metabolic turnover. The chapter on the protein S-100 has little relevance to metabolism (by any definition) and was rather tedious in its listing of conflicting reports on its properties and possible physiological role. Perhaps a general theme of this volume should have been the description of m;acromolecules found in the brain, i.e., nucleic acids, proteins (including transport proteins, brain specific proteins, glycoproteins, proteoglycans, and phospholipid-carrier proteins), and lipids. The importance of these substances in the metabolism, development, and assembly of brain structures coulci then have been discussed as subsections. In conclusion, the usefulness of Volume 5 as a whole is somewhat diminished by its haphazard arrangement. Volume 6 contains 24 chapters contributed by an international panel of experts. O n the whole, this volume is better organized than Volume 5. It contains excellent chapters on the pharmacological bases, physical characteristics, and neurological importance of the various classes and subclasses of receptors. In addition, this volume has chapters that include much useful information on topics that .are directly or indirectly related to receptor function and regulation, such as uptake and release processes for neurotransmitters, phospholipid methylation, protein phosphorylarion, and receptor adaptation to drugs. Chapter 14, “Cholinergic Systems and Cholinergic Pathology,” was somewhat out of place since it dealt mostly with the neuroanatomy of the cholinergic system and contained only three pages on the cholinergic receptor. There is also a certain amount of overlap and repetition which I believe could have been avoided, thus :shortening the book. For example, Chapter 8, “GABA Receptors,” contains several references to benzodiazepine binding and Chapters 10 and 2 1 are entitled “Benzodiazepine Receptors” and “Heterogeneity of Benzodiazepine Receptors,” respectively. One wonders why these chapters were so widely scattered and why they were not put together as a single chapter. 62 2 Receptor classification and terminology has become a very complicated and unwieldy area, partly because no two groups of investigators use exactly the same experimental conditions o r can agree among themselves on terminology. In describing the opiate receptors Eric Simon states “it appears likely to this reviewer [Simon) that much of the Greek alphabet will be used up for opiate receptor subclassification before the inevitable simplification from increased knowledge will come about.” Despite this pessimistic note, Volume 6 is on balance an excellent reference source OJI receptors in the central nervous System. ArthurJ. L. Cooper. MD New York, NY Brief Reviews by Fred Plum, MD Experimental Allergic Encephalomyelitis, A Useful Model for Multiple Sclerosis (Progress in Clinical and Biological Research, Vol 146) Edited by E . C . Alvord, Jr, M . W . Kies, A. .J.Suckling New York, Alan R. Lass, Inc, 1984 574 pp, illustrated, $68.00 This volume provides, in a remarkedly prompt manner. the proceedings of a symposium held in July, 1983. Its production has been achieved by photo-offset of typed copy, but illustrations are generally good. Sections include: (1) How good a model of MS is EAE today?; (2) Operating mechanisms producing demyelination; (3) Mechanisms controlling cell migrations; ( 4 ) Migrating cell populations; ( 5 ) Nonleukocytic mechanisms; (6) Antibodies involved in demyelination; (7) Myelin basic protein; (8) CSF studies; (9) Suppression of EAE and MS; (10) Other studies of EAE and EAN; and final summaries and discussions. Discussions have not been presented verbatim, but have heen summarized by respective chairpersons. The monograph appears valuable for all workers interested in multiple sclerosis from the standpoint of experimental evaluation and the search for effective treatment. Atlas of H u m a n Cross-Sectional Anatomy By Donald R . Cahill and Mattheu J . Orlrlnd Philadelphia, Lea & Febiger, 1984 139 pp, illustrated, $29.50 This well-produced new atlas by two anatomists from the Mayo Medical School in Rochester, Minnesota, and Department of Medicine of Washington University in St. Louis provides a valuable and well-prepared cross-sectional analysis of the human thorax, abdomen, pelvis, and head. Male and female pelvic organs are presented separately and the head is presented in two horizontal planes, one 20 degrees from and the other parallel to the orbitorneatal plane. Each page consists of a photograph of a cross section of the human body, frozen for purposes of preparation, with line drawings placed immediately above, providing more detailed contrast and extensive identification of the various structures. The material will be invaluable as a reference for the interpretation of modern tomographic imaging of both the bocly and head.