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Atlas of human cross-sectional Anatomy. By Donald R. Cahill and Matthew J. Orland Philadelphia Lea & Febiger 1984 139 pp illustrated $29

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Handbook of Neurochernistry
Edited by Abel Lajtha
New York, Plenum Press
Vol5, “MetabolicTurnozler in the Nervous System.”
495; pp, 1983
Vol6, “Receptors in the Nervous System,” 668 pi?, I984
Volume 5 contains 2 1 chapters contributed by authors from
the United States, Canada, and Europe. In general the individual chapters are carefully edited, well written, and interesting, and they provide useful information. However, the
title of Volume 5 is unfortunate and the chapters are not
organized in a logical sequence. Volume 3 in the series is
entitled “Metabolism in the Nervous System.” The similarity
of the titles is confusing. Surely “metabolism” implies turnover. Apparently “metabolic turnover” in Volume 5 is meant
to include protein translocation ( e g , retrograde and anterograde axonal transport) and uptake processes for hexoses,
amino acids, and other small molecules. Volume 5 contains
chapters on brain proteins (S-100, tubulin, nerve growth factor) in which there is little if any description of metabolic
turnover. The chapter on the protein S-100 has little relevance to metabolism (by any definition) and was rather tedious in its listing of conflicting reports on its properties and
possible physiological role. Perhaps a general theme of this
volume should have been the description of m;acromolecules
found in the brain, i.e., nucleic acids, proteins (including
transport proteins, brain specific proteins, glycoproteins,
proteoglycans, and phospholipid-carrier proteins), and lipids.
The importance of these substances in the metabolism, development, and assembly of brain structures coulci then have
been discussed as subsections. In conclusion, the usefulness
of Volume 5 as a whole is somewhat diminished by its
haphazard arrangement.
Volume 6 contains 24 chapters contributed by an international panel of experts. O n the whole, this volume is better
organized than Volume 5. It contains excellent chapters on
the pharmacological bases, physical characteristics, and
neurological importance of the various classes and subclasses
of receptors. In addition, this volume has chapters that include much useful information on topics that .are directly or
indirectly related to receptor function and regulation, such as
uptake and release processes for neurotransmitters, phospholipid methylation, protein phosphorylarion, and receptor
adaptation to drugs. Chapter 14, “Cholinergic Systems and
Cholinergic Pathology,” was somewhat out of place since it
dealt mostly with the neuroanatomy of the cholinergic system and contained only three pages on the cholinergic receptor. There is also a certain amount of overlap and repetition
which I believe could have been avoided, thus :shortening the
book. For example, Chapter 8, “GABA Receptors,” contains
several references to benzodiazepine binding and Chapters
10 and 2 1 are entitled “Benzodiazepine Receptors” and
“Heterogeneity of Benzodiazepine Receptors,” respectively.
One wonders why these chapters were so widely scattered
and why they were not put together as a single chapter.
62 2
Receptor classification and terminology has become a very
complicated and unwieldy area, partly because no two groups
of investigators use exactly the same experimental conditions
o r can agree among themselves on terminology. In describing the opiate receptors Eric Simon states “it appears likely
to this reviewer [Simon) that much of the Greek alphabet
will be used up for opiate receptor subclassification before
the inevitable simplification from increased knowledge will
come about.” Despite this pessimistic note, Volume 6 is on
balance an excellent reference source OJI receptors in the
central nervous System.
ArthurJ. L. Cooper. MD
New York, NY
Brief Reviews
by Fred Plum, MD
Experimental Allergic Encephalomyelitis,
A Useful Model for Multiple Sclerosis
(Progress in Clinical and Biological Research, Vol 146)
Edited by E . C . Alvord, Jr, M . W . Kies, A. .J.Suckling
New York, Alan R. Lass, Inc, 1984
574 pp, illustrated, $68.00
This volume provides, in a remarkedly prompt manner. the
proceedings of a symposium held in July, 1983. Its production has been achieved by photo-offset of typed copy, but
illustrations are generally good. Sections include: (1) How
good a model of MS is EAE today?; (2) Operating mechanisms producing demyelination; (3) Mechanisms controlling
cell migrations; ( 4 ) Migrating cell populations; ( 5 ) Nonleukocytic mechanisms; (6) Antibodies involved in demyelination; (7) Myelin basic protein; (8) CSF studies; (9) Suppression of EAE and MS; (10) Other studies of EAE and
EAN; and final summaries and discussions. Discussions have
not been presented verbatim, but have heen summarized by
respective chairpersons. The monograph appears valuable
for all workers interested in multiple sclerosis from the
standpoint of experimental evaluation and the search for effective treatment.
Atlas of H u m a n Cross-Sectional Anatomy
By Donald R . Cahill and Mattheu J . Orlrlnd
Philadelphia, Lea & Febiger, 1984
139 pp, illustrated, $29.50
This well-produced new atlas by two anatomists from the
Mayo Medical School in Rochester, Minnesota, and Department of Medicine of Washington University in St. Louis
provides a valuable and well-prepared cross-sectional analysis
of the human thorax, abdomen, pelvis, and head. Male and
female pelvic organs are presented separately and the head is
presented in two horizontal planes, one 20 degrees from and
the other parallel to the orbitorneatal plane. Each page consists of a photograph of a cross section of the human body,
frozen for purposes of preparation, with line drawings placed
immediately above, providing more detailed contrast and extensive identification of the various structures. The material
will be invaluable as a reference for the interpretation of
modern tomographic imaging of both the bocly and head.
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donalds, orlando, 1984, illustrated, atlas, matthew, cross, human, 139, philadelphia, cahill, anatomy, lea, sectional, febiger
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