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Book Review Advances in Structure Research by Diffraction Methods Vol. 2 Fortschritte der Strukturforschung mit Beugungsmethoden Bd. 2[] Edited by R. Brill and R

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however, has been enlarged and a chapter on “X-ray emission
spectrometry” has been introdaced. The latter is the only
chapter that does not describe experimental procedures, but
simply gives a description of the method and a list of references to applications in the steel industry.
The great value of the book lies in the description of proven
analytical methods, incorporating the experience of numerous
large laboratories of the steel industry. Rather surprisingly,
however, relatively little or no mention is made of a number
of more modern methods, such as polarography, X-ray
analysis, and atomic absorption. Moreover, there may be
some doubt as to the usefulness of the method given for the
determination of selenium.
The updating of this work in the new edition is very welcome,
and the book itself should take a n important place in the
library of any iron-foundry laboratory.
R. Bock
[NB 558 IE]
immune globulins and “paraproteins” in the widest sense;
finally light is thrown from various sources on autoimmunization, special emphasis being rightly placed on “immunovasculitis”. The choice of lecturers is excellent, and the discussions are terse and trimmed to the essentials. It may be
asked, however, whether it might not have been better to
translate the French contributions, for example one as important as that by Voisin, intm English. The overall presentation is such as to make the high price appear justifiable.
This book is more than mere leisure readin and it is recommended to the biochemist, who is nowadays faced to an
increasing extent with i m m u n o b i d ~ ~ l cquestions
as integral
parts of his own field. Some mpics, such as immunochemical
questions in the structure of proteins, will already be familiar
to him, and these will encourage him to turn to the apparently complex “immunobiological” phenomena, which are
presented here as a huge field of research.
C . Uhlenbruck
[NB 575 IE]
[*I For a review of Vol. 1 see Chemie-1ng.-Techn.36, 569 (1964).
Advances in StructureResearch by Diffraction Methods, Vol. 2
Fortschritte der Strukturforschung mit Beugungsmethoden,
Bd. 2 [*I Edited by R . Brill and R . Mason. Friedr. Vieweg
& Sohn, Braunschweig - Interscience Publishers, a Division of John Wilev & Sons. Inc., New York-LondonSydney 1966. 1st Edit., iii, 166 pp., 73 figures, 11 tables,
D M 34.--.
Progress reports of this nature fulfil a very important function
in scientific literature. They present a summary of the latest
results of special fields of research within a relatively short
time of the publication of the original papers. The book contains four articles written by experts.
On pages 1 to 33, G. E. Bucon discusses the investigation of
magnetic structures by neutron diffraction. Corresponding
to the great technical interest of this topic, very many publications have appeared; the author presents a good general
An important question is discussed in the article by R . Mason
and G. B. Robertson (Diffraction Methods and Quantum
Chemistry). The authors she+ how accurate X-ray analyses
(particularly accurate measurements of bond lengths and
angles) cawurovide experimental bases for quantum-mechanical calculations.
The longefit xficle ( D . C . Phillipsi Advances in Protein
Crystallography) deals with one af the most modern aspects
of X-ray structure analysis. I t alsoshows how quickly articles
of this type become out of date. For example, the latest work
by Phillips on lysozyme IS not included. However, it is still
very valuable because of its discussion of methods.
The last, short article by P . Corradini (New Results of Structural Researches on High Polymers) deals mainly with recent
work in the Italian high-polymer school.
W . Hoppe
[NB 572 IE]
[*] Vol. 1, cf. Angew. Chem. 77, 184 (1965); Angew. Chem.
internat. Edit. 4 , 175 (1965)
Immunopathology. IVth International Symposium, Monte
Carlo 1965. Edited by P . Grubar and P. A . Miescher.
Schwabe & Co.. Publishers. Basel-Stuttgart 1966. 1st.
Edit., 467 pp., 153 figures, 1 color plate, D M 80.-.
The present volume IV of the series o n immunopathology is
a fit companion for the earlier volumes, and needs no special
recommendation in expert circles.
The subjects discussed at this symposium were: The question
of tumor-specific antigens, and the closely related problem of
the histocompatibility antigens, the chemistry of which is
still largely unknown. A second lecture cycle deals with
The Amino Sugars. Vol. I1 B: Metabolism and Interactions.
Edited by E. A . Balazs and R . W. Jeanloz. From the series
“The Chemistry and Biology of Compounds Containing
Amino Sugars”. Academic Press, Inc., New York-London
1966. 1st Edit., xvii. 516 pp., numerous figures and tables,
8 22.00.
The latest contribution on the amino sugarsrll contains 14
chapters (38-51 in the consecutive numbering system), which
can be grouped according to subject. The first group (38-41)
deals with metabolic processes of the monomeric amino
sugars as well as of the polymeric compounds, the second
(42-47) with the enzymatic and non-enzymatic degradation
of glycosaminoglycanes, and the third (48-51) with the
relationships between amino sugars or polymers containing
amino sugars and various biological systems.
The individual topics discussed are: the metabolism of amino
sugars (E. A. Davidson), of glycosaminoglycans ( H . Bostrom,
L. Rode‘n), of glycoproteins, glycopeptides, and glycolipids
( I . Yamashina), the influence of steroid hormones o n the
glycosaminoglycans of secondary sex characteristics ( J . A .
Szirmai), hexosaminidases ( P . G. Walker), neuraminidases
( M . E. Rafelson j r . , M . Schneir, V. W . Wilson j r . ) , glycosaminoglycan-degrading enzymes ( H . Gibian) glycosaminoglycan sulfatases (K. S. Dodgson), activation and inhibition of
enzymes by polyanions containing amino sugars ( P . Bernfeld), chemical and physical changes of glycosaminoglycans
and glycoproteins by redox systems and irradiation (L. Sundblad, E. A . Balazs), interactions of polyanions with blood
components ( P . Bernfeld), immunochemisirj ( G . F. Springer),
interactions between glycoproteins afid vlruses (A. Gottschalk), and interactions between amino sugars or polymers
containing amino sugars and viruses cells, and tissues (E. A .
Bulazs, B. Jacobson
The literature is generally covered u p to 1963, and publications from 1964 and 1965 are listed as an appendix in some
chapters. In the article on amino sugar metabolism, the data
unfortunately d o not proceed beyond 1963, though numerous
papers o n this topic were published after 1963, particularly
in the bacteriological sector. H . Gibian’s chapter o n glycosaminoglycan-degrading enzymes is particularly well documented (up to 1965). Many of the articles also contain additional literature surveys on individual problems (e.g. o n the
incorporation of 35s into connective tissue and cartilage;
p. 52).
Like its predecessors in the series, the present volume again
demonstrates the importance of amino sugars in biological
systems. The authors d o not confine themselves to listing and
discussing results, but present detailed information about the
methods used and point out the advantages and disadvantages of certain techniques. (Gibian: hyaluronidase tests;
Walker: working-up of hexosaminidases; Springer: immunological techniques).
Angew. Chem. internat. Edit. 1 Vol. 6 (1967) No. 5
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