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Book Review New Techniques in Amino Acid Peptide and Protein Analysis. Edited by A. Niederwieser and G

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cite almost exclusively original sources in English)
provide an opportunity for further reading on the topics
The description of recent developments and refinements
and the treatment of numerous nuclei that were formerly
not very common will provide stimulating material in
particular for structural analysts and NMR spectroscopists.
The presence of a number of gaps in the sections is unavoidable in view of the flood of literature and the rapid
development of NMR spectroscopy.
Eberhard Breitmaier
[NB 121 b IE]
a well coordinated manner. The monograph should be
a very valuable aid to all biologists, chemists, and toxicologists concerned with phytopathology and microbiology,
and should also provide a stimulus to close the gaps,
someofthem considerable, that still exist in our knowledge
of the mode of action of fungicides.
Kfaus Sasse
[NB 141 IE]
The Raman Effect. Vol. 1. Principles. Edited by A. Anderson.
Marcel Dekker, Inc., New York 1971. 1st ed., ix, 404
pp., numerous figures, bound $ 28.50.
A fundamental survey of the theoretical and experimental
New Techniques in Amino Acid, Peptide and Protein Analysis. Edited by A . Niederwieser and G . Pataki. Ann
Arbor-Humphrey Science Publ., Inc., Ann Arbor Mich.
1971. 1st ed.,461 pp., numerous figures a d tables. bound
$ 22.50.
The rapid development of a field of science is almost
inevitably linked with the development and introduction
of new procedures. Thus the biological sciences brought
with them considerable advances in chemical methods.
The present book, or more precisely its first eight chapters,
summarizes new experimental methods in the field of amino
acids, peptides, and proteins: 1. ion-exchange chromatography of amino acids and peptides; 2. and 3. gas chromatography ofamino acids and peptides (these two chapters overlap
to some extent);4,mass spectrometry of peptides;5.molecular sieve chromatography; 6. thin layer gel filtration ;
7. microelectrophoresis and synthesis of proteins in quantig ; 8. protein electrofocusing. The
ties of lo-’ to
last two chapters (chemical accessibility and environment
of amino acid residues in natural proteins and methods
for the study of the quaternary structure of proteins), on
the other hand, are surveys of methods with fairly superficial descriptions of techniques.
The editor has allowed the authors an individual approach
to their own chapters. Overlapping occurs in places. However, the book as a whole will be successful in the editor’s
aim of presenting reliable surveys of the new experimental
Karel BLLiha [NB 138 IE]
Chemistry of Fungicidal Action, Molecular Biology, Biochemistry, and Biophysics. By R. J . Lukrns. Springer-Verlag, Berlin-Heidelberg-New York 1972. 1st ed., xiii,
136 pp., 8 figs., bound DM 42.-
The present monograph presents a comprehensive survey
of current knowledge on the chemistry of fungicides that
are used for the protection of plants or industrial organic
materials against destructive fungi. Its purpose is to explain
general and common principles of fungitoxic phenomena
within the framework of present-day views in cell biology.
The material is divided into the following sections: 1.
chemical control of deterioration by fungi (3 pp.), 2.
measurement of fungitoxicity (8 pp.), 3. fungitoxic barriers
(18 pp.), 4. migration of fungicides to sites of action (8
pp.), 5. sites of action (17 pp.), 6. reaction of fungicides with
cell constituents (11 pp.), 7. effects of fungicides on enzymes
(9 pp.), 8. structure-activity relationships (15 pp.), 9. action
of fungus on fungicide (8 pp.).
The formulas of the fungicides discussed are listed in a
seven-page appendix.
The discussion is based on details from 460 references,
whose main conclusions are presented succinctly and in
principles of the Raman effect and of its important applications in physics and chemistry is to be presented in two
volumes. The book is intended for students and scientists
seeking an introduction to the field of Raman spectroscopy.
Volume 1 contains the following chapters: 1: Historical
Introduction ( R . S. Krishnan, 48 pp.), a rather long-winded
account for the intended readership, with only a few tables,
formulas, or critical comments. For example, a half page
on “Born’s Lattice Dynamics” is followed by a page on
“Raman’s Lattice Dynamics”, with no indication for the
beginner of the problem involved in this controversy and
with no objective comparison. Chapter 2: Polarizability
Theory of the Raman Effect (G. W Shanrry, 47 pp.) and
Chapter 3: The Theory of the Raman Scattering of Crystals
( R . A. Cowiey, 87 pp.) are worth reading, particularly for
physicists. Chapter 4 : Raman Instrumentation and Technique (C.E. Hathaway, 104 pp.) gives a detailed account
of the properties of gas discharge lamps, spectrographs,
and photographic plates and of commercial instruments
that have long since fallen out of use or been withdrawn
from the market, together with detailed information on
laser light sources and modern spectrometers. This is followed by Chapter 5: Stimulated Raman Effect (P. Lallernand, 56 pp.) and Chapter 6: Brillouin Scattering ( R . S.
Krishnan, 61 pp.), both of which are very good descriptions,
which will be of interest in particular to the physicist.
The readers at which the book is aimed would find it
more useful if Chapters 1 and 4 were dusted off somewhat
and provided with critical comments. The present volume
has little to offer the chemist. The applications in the
fields of chemistry and physics are to be presented in
Volume 2.
Brrnhard Schrader
[NB 144 IE]
Mechanism in Organic Chemistry. By R. Alder, R. Baker,
and J . M . Brown. John Wiley & Sons, Inc., New YorkLondon 1971, 1st Edit., x, 378 pp., numerous figures,
bound f 5.00.
The main purpose of the authors was to summarize in
one volume the present situation in mechanistic organic
chemistry for advanced students. They assume that
the student is familiar with a textbook of organic chemistry (such as that by Roberts and Caserio) and that he
has been introduced to the principles of physical chemistry.
The aim of the book is to enable the reader to understand organic reaction mechanisms, to allow critical
reading of original articles in this field, and ultimately to
enable him to plan and execute his own experiments
The actual treatment of organic reactions is preceded by a
general chapter, in which catalysis, the energies of ground
and transition states, and isotope, ring-strain, solvent,
steric, electronic, and stereoelectronic effects are discussed.
A n y e w Chem. m t u m a f . Edit.
Vol. 12 (IY73)
i No. 8
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