[51 ( 5 1 and DzO were mixed in a molar ratio of4:96; the mixture ([D2]-(5), [Di]-fS), ( 5 ) ) formed by exchange was distilled into the reaction flask under argon and lithiated to give a mixture of [ D i ] - ( I ) and ( I ) as. in [Z] but with excess butyllithium so as to convert any entrained DIO. HOD. H 2 0 into LiOD and LiOH. O n complete exchange with the DIO. without D,#Hexchange during distillation, and neglecting kinetic 161 isotope elfects in the lithiation [ I l l ] - ( / ) and ( 1 ) diould have been formed in a molar ratio of 96:J. L. Birkofir. A . Ritter. Angew. Chem. 77. 414 (1965): Angeu. Chem. Int. Ed. Engl. 4, 417 (1965): L. Birkofir, N. Dickopp, Chem Ber. 101, 3579 (1968). BOOK R E V I E W S Optoacoustic Spectroscopy and Detection. Edited by Yolz-Hun Pao. Academic Press, New York-London 2977. xi, 244 pp.. numerous figs., and tables, bound, S 29.00. Optoacoustic or photoacoustic spectroscopy is one of the most recent procedures in instrumental analysis, although the underlying physical phenomenon was reported as long ago as 1880 by Alexander Graham Bell. It is a variant of classical absorption spectroscopy in the UV/visible and IR regions, in which a microphone is used as the detector. This combination of optics with acoustics has led to the designation optoacoustic or photoacoustic spectroscopy. In this, the first monograph on the new procedure nine authors, including L. B. Kreuzer and A. Rosencwaig who are accounted pioneers in the field, report on the physical principles, design of the apparatus, and the possible applications, in eight independent chapters each with its own bibliography. An introductory chapter on signal production and detection is followed by sections on energy transfer, the principles underlying the optoacoustic spectrometer, on tunable light sources in the UV/visible and the IR region, and on the optoacoustic spectroscopy of gases and solids. The individual chapters are very clearly written and are provided with a wealth of illustrations. The literature review is probably the most complete that exists at present for this field. The book can be recommended to all who are interested in this new process of instrumental analysis and are active in teaching and research or in the application of this area of absorption spectroscopy. Egon Fuhr [NB 438 IE] Principles of Colloid and Surface Chemistry. By P. C. Heimenz. Undergraduate Chemistry: A Series of Textbooks, Vol. 4. Marcel Dekker, New York-Basel 1977. 1st edit., xi, 516 pp., bound, SFr. 64.00. Important aspects of the extensive field of colloid chemistry are treated in eleven chapters with the physical considerations placed in the foreground. After the introduction of the important experimental values, Chapters 1-4 give an extensive treatment of viscosity, sedimentation, and diffusion (the fundamental mathematical derivations are given in every case), and a discussion of osmotic phenomena. Chapter 5 discusses light scattering theoretically and with numerous experimental examples. There follow chapters on surface tension and adsorption from the liquid phase, starting consistently with the Gibbs equation. The descriptionofadsorption isothermsisplaced as thecentral point of Chapter 8, which deals with adsorption from the gas phase. Unfortunately, this chapter is confined to physisorption, whereas in view of the demanding title of the book at least a brief illustration of the very important area of chemisorption could have been expected. Chapter 9 is devoted to electrochemistry (electrode processes, Debye-Huckel and 86 Gouy-Chapman theory), while van der Waals interaction and its significance for flocculation phenomena of colloidal particles are treated in Chapter 10. The final chapter contains information on electrophoresis and other electrokinetic phenomena. All in all, the book covers an astonishingly wide field and offers many details; it is forcefully and clearly written, but also includes strict mathematical derivations wherever these are necessary. It is designed for chemists who wish to enter the field of colloid chemistry, though specialists too will find the occasional useful detail. Klaus Christnzann [NB 439 IE] Methodische Fortschritte irn medizinischen Laboratorium (Progress in Methods used in the Medical Laboratory). Vol. 3: Akute Syndrome (Acute Syndromes). Edited by A. Englhardt and H . Lommel. Verlag Chemie, Weinheim-New York 1978. 1st edit., viii, 288 pp., 35 figs., 138 tables, plastic, DM 62.00. It is unfortunate that the subtitle “Laboratory diagnostics of acute internal diseases” does not appear on the cover, for what is the uninformed or even just the curious reader to make of an “acute syndrome”? Certainly not a “group of related acute symptoms” as given in textbooks and dictionaries. In their foreword the editors indicate that the plan of the book was based on the following concepts: 1. All modern methods of an emergency laboratory are to be treated. 2. The book should be a reference work for acute situations that call for rapid treatment. 3. Detailed references should provide a review of clinical symptoms, diagnoses, and differential diagnoses. 4. Clearly laid out tables should give side by side clinical pictures and laboratory investigations. The book contains the following chapters, written by a number of individual authors: acute endogenous intoxications, acute exogenous intoxications, acute cerebral processes : apoplexy and its differential diagnosis, acute disturbances of the cardiovascular system, acute disturbances of hemostatis: acute bleeding, acute disturbances in the abdominal region : the acute abdomen, acute inflammatory organ disorders, acute disturbances of the defense system against infections, acute hemolytic crisis. It must be emphasized that the clinicochemical part determines the value of the book. All essential data on methods are described in detail or references are given to customary test methods. In view of the progress in the field of clinical chemistry this method of presentation will soon make necessary a supplementary volume or even a new edition.