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Book Review Quantitative Management in R & D. By C. J. Beattie and R. D. Reader

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Mass Spectrometry of Heterocyclic Compounds. By Q. N .
Porter and J . Baldas. John Wiley and Sons, London-New
York 1971. 1st Edit., xvii, 564 pp., numerous figures,
bound E 11.75.
The importance that mass spectrometry has acquired in
organic chemistry in recent years has led to such a spate of
primary literature, distributed through a wide range of
journals under a variety of titles, that an overall view of the
field is becoming increasingly elusive. The related difficulty
of becoming acquainted with even a restricted range of
material or of merely keeping abreast of recent developments often has the result that the possibilities of mass
spectrometric analysis are not fully exploited. Good secondary literature has therefore become a conditio sine qua non.
With this in mind the authors of the present work have
turned their attention to an area of study that was in desperate need of a critical assessment and survey, i.e. mass
spectrometry of heterocyclic compounds. The effect of the
ring system on the general fragmentation behavior in
various environments is discussed on the basis of ring size
and the natureand the number ofheteroatomsand illustrated by numerous examples of spectra. Although the subject
matter is extremely heterogeneous, in spite of being limited
to saturated and unsaturated N, 0, and S heterocycles, the
description of the individual structural types is both detailed and, particularly, not uncritical, thus obviating the need
to refer back to the original literature in many cases. It
would have been better, however, if the relative intensities
of the fragments had been listed more consistently.
Generally speaking, the relevant literature has been covered
in considerable detail (apart from papers in the Russian
language) although examples from the field of natural
products (particularly alkaloids) are included only when
they are characteristic of the behavior of a particular fundamental skeleton in a specific environment. Unfortunately, and this remark concerns more the publisher than the
authors, more than three years seem to have passed between completion of the manuscript (the literature is
evaluated up to 1967) and appearance of the book, and
research has by no means stood still during this time; the
brief addenda at the end of each chapter, which provide a
survey of the most important publications up to 1970, are
rather inadequate.
Neverthe1ess:the present book is not only a great help to the
mass spectroscopist as far as information content and a
solid basis for further literature searches are concerned, but
it also provides the organic chemist with an overall picture
of where he can profitably apply mass spectrometry in the
wide field of heterocyclic chemistry. It is to be hoped that
supplementary volumes surveying the latest developments
will appear at regular intervals.
Herbert Budzikiewicz [NB 44 IE]
Quantitative Management in R &D. By C. J. Beattie and
R.D.Reader. Chapman and Hall Ltd., London 1971.
1st Edit., x, 347 pp., numerous figures, bound E 5.00.
The use of quantitative methods to increase the profitability of research and development has been attracting increasing interest in recent years even though the objective
value of such methods is still disputed. Although the knowledge hitherto collected has long been the subject of numerous seminars organized by consultant companies the
publication of the present book is to be welcomed. The
authors have presented the current situation in an extreme648
ly understandable and purposely simplified manner in
order to assist the reader in familiarizing himself with the
subject matter. Anybody who wishes to deIve deeper into
the methods described can refer to the highly informative
appendix and to the exceptionally detailed bibliography
at the end of each chapter.
The book opens with a brief introduction (5 pages) to the
essential phases of a research project followed by a chapter
on the generation of useful ideas (12 pages) which describes
special methods such as “brainstorming” and also more
conventional practices such as the cooperation between
colleagues from different disciplines.
There follows a chapter on the planning of research projects (30 pages) which is concerned with the preparation
required for the evaluation of a project. The most important diagrammatic planning techniques are briefly considered. The chapter on project evaluation itself (38 pages)
discusses in how far the intuitive assessment of suggestions
can be supported by analyses of the expected costs on the
one hand and the expected economic advantage on the
other.
This kind of numerical assessment is a prerequisite for
choice of research projects as considered in the next chapter (48 pages). The methods described range from simple
classification on the basis of a more or less suitable parameter to relatively complicated processes requiring access
to a computer.
Further chapters essentially provide practical instructions
for the application of such systems of choice (together 40
pages) and for the execution and control of research projects (13 pages). Particular emphasis is placed on the writing
of suitable reports on the results of studies (34 pages).
The appendix contains detailed information about methods
of technological forecasting (20 pages), diagrammed planning techniques (55 pages), discounted cash flow calculations
(9 pages), and uncertainty analyses (21 pages). An index
makes for easy reference to the book.
Peter Haug [NB 45 IE]
The Avenue of Years-A Memoir of Sir James Irvine. By
Mabel K Irvine. William Blackwood, Edinburgh and
London 1970. 1st Edit., iv, 268 pp., 9 figures, bound
E 1.80.
Sir James Colquhoun Irvine (1877-1952) was Professor of
Chemistry at St. Andrews, Scotland, from 1909 to 1920,
and was then Principal and Vice Chancellor of this university from 1921 to 1952. He is one of the leading figures
of Scottish university history and was well known far beyond the boundaries of his country. As a chemist he was
active in the field of carbohydrate chemistry and among
other achievements he introduced the methylation of hydroxyl groups as an aid in the structural elucidation of
carbohydrates.
Irvine’s wife, who survived her husband by 15 years,
authored the present biography which remained uncompleted and does not extend beyond 1944. The book is not an
historical work, and makes no pretence to be one, but
rather a very personal series of recollections. The authoress
describes family life, social obligations, the atmosphere of
the small Scottish university town steeped in tradition,
Irvine’s administrative activities, and his numerous journeys abroad in his capacity as Principal.
Unfortunately the reader learns next to nothing about
Irvine’s research as a carbohydrate chemist, which was
Angew. Chem. internat. Edit. 1 Vol. I 1 (1972) 1 No. 7
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