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Book Review Reaktionen der organischen Chemie (Reactions of Organic Chemistry). By H. Krauch and W. Kunz. 5th revised and extended edit. By W. Kunz and E

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which the free enzymes undergo undesirable side reactions
(association,self consumption). Furthermore, biologically relevant model systems can be constructed, for enzymes are not
freely mobile in their natural environment but are bound
to membranes or surrounded by a gel-like phase. In addition,
immobilized enzymes are gaining increasing importance for
preparative and analytical purposes. Immobilized coenzymes
have general utility as affinity adsorbents. [Immobilized
Enzymes. FEBS Lett. 62 (Suppl.), Eg(tE95 (1976); 84 references]
[Rd 909 IE-RJ
DNA ligases of eukaryotes are reviewed by S. Soderhall and
7: Linduhl. Theseenzymes act together with the DNA polymerases in replication and the repair of strand breaks. Mammalian
enzymes differ from the better known enzymes of microorganisms. Thus, only ATP has been detected as energy donor,
whereas bacterial enzymes also use NAD’. In contrast to
microorganisms, mammalian cells contain two different DNA
ligases. The dominating enzyme I is relatively large (175200000 Dalton) and occurs mainly in dividing cells. It can
couple growing DNA fragments in vitro. Enzyme 11, with
a molecular weight of 85000 Dalton, occurs only in small
amounts (5-20%). It is less specific than enzyme I. A
ligase similar to enzyme I1 has also been detected in mitochondria. [DNA Ligases of Eukaryotes. FEBS Lett. 67,l-8 (1976);
73 references]
[Rd 911 IE-R]
A review of methods for the analysis of kinetic data in biochemistry is given by M . Markus, B. Hess, J . H. Ottaway, and
A . Cornish-Bowden. The review is based on discussions held
at a conference devoted to this theme. The advantages and
disadvantages of the total trace of the curve as well as the
various methods for the linearization of kinetic functions are
discussed. [The Analysis of Kinetic Data in Biochemistry.
A Critical Evaluation of Methods. FEBS Lett. 63, 225-230
(1976); 59 references]
[Rd 910 IE-R]
Werkstoff Glas (Glass as a Material). By K . Kiihne. AkademieVerlag, Berlin 1976. 1st edit., 329 pp., various figs., paperback, cu. 12.50 DM.
The history of glass goes back many thousands of years.
Scientific penetration into glass technology began at the end
of the nineteenth century (e.g. by Schott at Jena), but one
can validly speak of a science of glass only from about 1950.
Today glass with almost any desired properties can be made.
After a short section ofthe history of glass the book discusses
“the vitreous state”, in which, inter a h , views on the structure
of glass and its segregation are discussed. The following chapter
describes the glass-forming systems and applications of glass,
while Chapter 4 concerns the properties of glasses and the
possibilities of their modification. The next (very extensive)
chapter deals with the production and working of glass. Finally
there is a short section on “Special Glasses”, followed by
literature references and several indexes.
The author has succeeded in giving a very good and easily
readable review of the field. The presentation is perhaps a
little too classical, and in some places one could have hoped
for the latest results obtained by modern methods of investigation. Nevertheless, the book can be very warmly recommended
to all interested in glass, e.g. to students at universities or
technical colleges and to scientists in industry.
G. H. Frischat [NB 356 IE]
Reaktionen der organischen Chemie (Reactions of Organic
Chemistry). By H. Krauch and W Kunz. 5th, revised and
extended edit. By W Kunz and E . Nonnenmacher. Dr. Alfred
Hiithig Verlag, Heidelberg 1976. xxxi, 875 pp., linen, D M
The original “Named Reactions” title of “Krauch-Kunz”
was generalized to “Reactions of Organic Chemistry” already
in the 3rd edition (1966), when some important reactions
not known by their discoverers’ names were added, with brief
descriptions and literature references. In the present 5th edition
Anyun. Cliem. 1m. Ed. Enyl. 16 ( 1 9 7 7 ) N o . 1
this tendency to broaden the scope has led to a changeover
from the mode of arrangement by authors’ names to arrangement by the description of content. For example, the degradation processes of carboxylic acids due to Barbier- Wieland,
Gallayher-Hollunder, Kraft, and Miescher are no longer scattered all over the text but are treated one after the other (pp.
21 6ff.). Simultaneously with this rearrangement, the authors
have tried to make the reaction terminology more standardized, with dubious success, judging by the lack of consistency
in the descriptions selected. Thus, the degradation of carboxylic
acids according to Simonini and to Hunsdiecker-Borodin is
treated under “Decarboxylation of Silver Salts” (p. 700), and
ring syntheses from a,o-difunctional alkanes are discussed
in one place as cyclization (Gustauson-Hass, p. 302) and in
another as ring closure (Ladenburg, p. 687), and finally also
as propane ring closure (Freund, p. 650), starting from the
educt. Fortunately, the volume contains not only an extensive
author and subject index but also an index of named reactions,
so that “Krauch-Kunz” can still be used, as before, for reference to a reaction under its “trivial name(s)”.
Along with the new principle of arrangement in the 5th
edition, some of the descriptions of the reactions have been
revised and the references have been extended, apparently
to the end of 1974. Only 15 new reactions have been added
among the present total of ca. 580. Even if we allow that
the choices made by the authors must necessarily be subjective,
we may surely ask whether the last ten years have not brought
forth a larger number of “named” reactions which at the
same time supersede older processes. In this respect the current
revision has not always succeeded in eradicating the patina
of age. This also appears in the often old-fashioned nomenclature, although actual errors, such as the description of the
bicyclobutonium ion by mesomerism of two cations (p. 686),
are refreshingly rare. In all, value of “Krauch-Kunz” as a
revision text has decreased, but for rapid information about
a reaction, and for gaining an entry into the primary and
secondary literature, this volume remains irreplaceable.
Ernst Schaumann [Nb 357 IE]
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