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Book Review Synthetic Nucleotides. Vol. 1. By G. R. Pettit

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Synthetic Nucieotides. Vol. 1. By G. R. Pettit. Van Nostrand
Reinhold Comp., New York-London
1972. 1st ed., viii,
252 pp., bound L 10.00.
In this book, G. R. Pettit presentsa long-needed comprehensive
tabular survey of synthetic nucleotides
All the important nucleotides mentioned from 1945 to June
1971, together with their methods of synthesis, are discussed
in nine chapters, starting with the mononucleotides having
the bases U, C,T, A, and G and their derivatives and proceding
via theoligonucleotides to the polynucleotides. In each chapter
the tables are preceded by brief descriptions and formulas
for well-planned and well-proven syntheses.
In addition to the literature references, each table contains
a brief outline of the phosphorylation method and information
about the solvent and the chromatographic procedure. UV
values, melting point, and yield are given. The tables also
show whether R, values, electrophoresis values, and elemental
analyses are given in the original literature for the characterization of the nucleotides and what spectroscopic methods
and enzymatic tests have been used.
The author has put a great deal of work into separating
the wheat from the chaff in the nucleotide chemistry literature
of the past 25 years, some of which is rather obscure. It
is pleasing to know that the author intends to continue this
work in the same way as his “Synthetic Peptides”. It should
be pointed out, however, that the present book has a number
of shortcomings, both with regard to its content and of a
technical nature.
In a book that claims complete coverage of the results of
the last 25 years, the number of references (barely 350) is
far too small. Furthermore, a good 10 *Aof these are connected
with the historical discussion in the introductory chapter.
The author rightly criticizes the fact that the characterization
ofthenucleotides is often based on faith. It is therefore difficult
to understand why he does not cite articles in which abundant
use is made of enzymatic and spectroscopic techniques. Moreover, the table should also give experimental values from other
publications. Another desirable feature would have been references to other recent important reviews.
Despite these reservations, the book should certainly be very
useful to nucleotide chemists and to chemists who wish an
insight into this field. It should find a place in any library.
K a y Schattka
[NB 176 IE]
The Scientific Principles of Crop Protection. By H. Martin.
Edward Arnold, London 1973 6. Edit., VIII, 423 p., bound
f. 12.-.
Contents: Plant Resistance; External Factors; Biological
Control; Pesticides: Measurement and Mechanics of Toxicity;
Fungicides; Insecticides ; Herbicides; Fumigants; Seed
Treatment; Soil Treatment; Traps; Centres and Vectors of
Infection.
Analytical Chemistry of Neptunium. By V . A . Mikhaiiou.
From the series “Analytical Chemistry of the Elements”.
Edited by A . P. Vinogradou. Israel Program For Scientific Translation, Jerusalem-London/Halsted Press, New
York 1973. VII, 235 pp., bound f. 9.35.
Contents: Separating Neptunium from Foreign Elements;
Quantitative Determination of Neptunium.
Coordination Chemistry - XIV. Edited by the International Union of Pure and Applied Chemistry in collaboration
with the National Research Council of Canada and the
Chemical Institute of Canada. Symposium Editor: A. B. P .
Lever. Butterworths, London 1973. 651 pp., bound E4.50. Plenary lectures at the XIV. International Conference on
Coordination Chemistry, 22-28 June 1972 in Toronto/
Canada.
Chemistry of Marine Natural Products. By P. J. Scheuer.
Academic Press, New York-London 1973. XI, 201 pp.,
bound $ 14.00.
Contents: Isoprenoids; Sterols; Benzenoids; Nitrogenous
Compounds; Nonaromatic Compounds with Unbranched
Carbon Skeletons.
Advances in Quantum Chemistry, Voi. 7. Edited by P.-0.
Luwdin. Academic Press, New York-London 1973. XVI,
445 pp., bound $29.50.
Registered names, Imdemarks, etc. used m rhis journal, ecen without speclfic indicatron thereo/, are not to be consrdered unprofected by Ian.
0Verlag Chemie GmbH, Weinheim 1974
-Printed in Germany by Zechnersche Buchdruckerei, SpeyerIRhein.
All rights reserved (Including those of translation into foreign languages). N o part of this issue may be reproduced in any form - by photopnnt, microfilm, or any other means - nor transmitted or translated into a machine language without written permission from the publishers.
Editorinl office: Boschstrasse 12, 6940 Wemheim/Bergstr., Germany, Telephone 403614037. Telex 4655 16 vchwh d.
Editor: H. Crijnewald Translation Editors: A . J . Rackstraw and A. Sttmson.
Publishers: Verlag Chemie GmbH. (Managing Directors Jiirgen Kreuzhoge and Hans Schermer) Pappelallee 3, 6940 Weinhem/Bergstr.. Germany, and Academic Press Inc. (President Charles
Huff), 111 Fifth Avenue, New York 3, N.Y., USA. and Berkeley Square House, Berkeley Square, London, W. l . , England.
Correspondence concerning advertisements should be addressed to Verlag Chemie GmbH. (Advertsing Manager H Both). 6940 Wemheim.Bergstr., Pappcldllee 3 . P 0. Box 1260/1280
Germany, Telephone Weinheim (06201) 4031, Telex 4655 16 vchwh d.
96
Angew.
Chem. internat. Edit. / Vol. 13 ( 1 9 7 4 ) / No. I
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