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Book Review Synthetic Peptides. Vol. 1. By G. R. Pettit

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BOOK R E V I E W S
Synthetic Peptides. Vol. 1. By G. R. Pettit. Van Nostrand
Reinhold Co., New York-London 1971. 1st Edit., xii,
467 pp., numerous tables, E 10.00.
ples contributes to an improved understanding without
making too severe demands on the mathematical knowledge of the reader.
One of the chief problems for workers in the field of synthetic chemistry is to find out as quickly as possible whether
the substance in question has already been prepared, and
if not, the way in which substances of similar structure can
be obtained. This is particularly troublesome in the case of
bio-oligomers, and therefore peptides. Specialized handbooks in which substances that have already been characterized are brought together are thus extremely useful.
A brief introduction to the typical dynamic behavior of
processes and the basic dynamic models derived therefrom
is followed by four chapters on the mode of action of a
regulator and the regulatory processes employed in
practice, ranging from the simple control loop to the control
of multi-loop systems with many variables. A short chapter
is devoted to the functioning of analog computing modules
and their practical use in switching operations.
The present book, which covers the period 1960-1969,
links up with earlier reviews of similar nature (e.g. Goodman
and Kenner 1957, Greenstein and Winitz 1961). The great
upsurge in peptide synthesis has resulted in the fact that
practically the entire volume consists of tables on aminoacid derivatives and di- to polypeptides. Physical constants
(m. p.,
and synthetic routes are included. In some cases
the tabulated data have been critically selected. For the
derivatives this evaluation agrees with the experience of
other peptide chemists, except that the o-nitrobenzenesulfenyl protective group may not have been ranked highly
enough. Not all compounds of a given type are included in
the tables, but random sampling in the reviewer’s laboratory
showed that only a few compounds have been overlooked.
The most important chapter, and also a particularly
valuable aspect of the book, is doubtless the following one
on dynamic behavior and control systems of process plant.
Current knowledge of the dynamics of the most important
groups of equipment in chemical production plant-heat
exchangers, distillation columns, and reactors-is surveyed, and proven circuitry is demonstrated, and, insofar
as is possible, critically discussed. The experienced control
engineer will also find this chapter stimulating, due in part
to the numerous literature references which will be a great
help to further study.
[XI)
The number of printing errors etc. is not outside the limits
expected for a work as ambitious as these tables. The only
thing that may bother the reader is the inconsistent use of
abbreviations; in many cases these differ from the ones
given in the introduction. Some compounds are not in the
proper order (e.g. pp. 366,425).
This book will be a useful aid to all chemists concerned
with peptide synthesis.
Karel Blaha [NB 39 IE]
Regeln und Steuern. Eine Einfiihrung fur Chemiker und Ingenieure (Regulation and Control. An Introduction for
Chemists and Engineers). By A. SchGne. Verlag Chemie
GmbH, Weinheim/Bergstrasse. 1971, 1st Edit. viii,
207 pp., 136 figures, 8 tables, bound DM 33.-.
The high degree of automation of chemical production
plants inevitably confronts chemists and engineers involved in process development and operation with problems
of control engineering. The purpose of the present book
is to provide this group of persons with an account of the
fundamentals of control engineering and to explain the
regulatory function of control circuits frequently encountered in practice. The author therefore places the main
emphasis on the process, and in particular the dynamic
behavior of processes, and has consciously renounced any
attempt to present a complete account of the theory of
control or measuring techniques which usually occupy a
large part ofmonographs on control engineering. The many
standard terms of control engineering are not presented
en bloc in an introductory section, as is usually the case,
but introduced almost in passing in the individual chapters, a feature which will certainly facilitate their assimilation. Fundamentals are explained with the aid of simple
and illustrative examples presented as block circuit diagrams ; the occasional analytical treatment of these examAngew. Cliem. internat. Edit. 1 Vol. 11 (1972) 1 No. 7
In view of the present-day significance of fully automated
control of batch processes in chemical process engineering,
the next chapter on control could have been more detailed.
The book closes with a chapter on process computers, in
which a terse review of the mode of action and process periphery of computers precedes accounts of direct digital
control (DDC) and process optimization.
The book is a highly successful, practically oriented introduction to control engineering that can be warmly recommended to production chemists and engineers, as well
as to control experts.
Theo Ankel [NB 42 IE]
Essential Fiber Chemistry. By M . E. Carter. Marcel Dekker
Inc., New York 1971. 1st Edit., vii, 216 pp., numerous
figures, bound $ 19.50.
No such book has hitherto been available. Its appearance
is most welcome, particularly in view of its numerous virtues, and will certainly satisfy a need of all those having an
interest in fiber chemistry. The book presents a didactically
exemplary introduction to the chemistry and physics of
natural and synthetic fibrous materials. The description of
fundamental principles of chemical and physical structure
and their relation to the most important properties of
fibers is completely devoid of such ballast as the various
techniques available for working the fibers. Interesting
indications of new developments and fiber modification,
particularly with regard to dyeability, flame resistance, and
temperature resistance, round off the survey of an interesting area of modern organic and macromolecular chemistry.
In spite of a certain degree of criticism with regard to
unnecessarily extensive tables of patents, the preference for
American literature, and the absence of any assessment of
the technical and economical viability of certain processes, the book can be warmly recommended to textile
chemists and all those who were unable to devote suficient
attention to this field as students.
Giselher Valk [NB 43 IE]
647
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