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Book Review The Acridines. Their Preparation Physical Chemical and Biological Properties and Uses. By A

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tained with the aid of the cited literature. “Rompp” does
not just have a place in every library - it is a miniature
library in its own right.
H . Grunewold
[NB 646 IE]
Technisches Taschenvcorterbuch (Pocket Technical Dictionary), English-German, German-English. By H . G. Freeman.
Max Hueber Verlag, Munich 1965. 2851297 pp., soft cover,
DM 9.80 each volume.
When one reads in the foreword to a dictionary that “Nearly
every engineer needs - rightly and properly - to consult a
technical dictionary from time to time. Such dictionaries ....
should not confront the user with a crossword puzzle in every
7 out of 8 renderings”, then one is dealing either with a very
good dictionary, or else with a very self-confident author.
After looking through these two volumes, the reviewer has
gained the impression that the latter alternative is the more
likely. Or is it not, perhaps, a “crossword puzzle” to find without any distinction being drawn - “waste, refuse; decrease, drop” for “Abfall”, or “outlet, discharge; outflow; expiration” for “Ablauf”? The engineer seeking to satisfy his
“right and proper” needs will be disappointed, for a list of
such puzzles would run right through the alphabet.
A good solution has been found to the problem of composite
words: to avoid long lists of similarly formed words, the
author in each case quotes only the first part of such words,
illustrating its use with a few examples. This enables both
volumes to remain compact at no cost to the information
by dehydrating agents). This gives a very clear presentation
of the extensive material covered. The consistent application
should be encouraged whenever possible in subsequent volumes. This bolume with numerous references, which also
include early publications as well as reviews (mostly up to
1963), is a valuable source of information which no organic
chemistry laboratory should lack. Print and presentation
are excellent.
K . Hafner
[NB 609 IE]
[*] Cf. Angew. Chem. 78, 397, 398 (1966); Angew. Chem. inter-
nat. Edit.
433, 434 (1966).
The Acridines. Their Preparation, Physical, Chemical, and
Biological Properties, and Uses. By A . Albert. Edward
Arnold (Publishers) Ltd., London 1966. 2nd Edit., xii, 604
pages, numerous figures and tables, 168 s.
Because of the inclusion of many new results in the acridine
field, the 2nd edition of this book is almost twice as large as
the first edition (1951). The grouping of the material is the
same as in the previous edition, the preparation, the physical,
chemical, and biological properties, and the many uses of the
acridines being discussed in five sections. It should be mentioned that the C atoms and the N atoms of the acridine ring
are numbered in accordance with the IUPAC recommendations, with the result that earlier confusion with regard to the
positions of substituents has now been eliminated.
[NB 582 IE]
The first eight chapters deal from the practical angle with the
methods of synthesis known u p to September 1965. The most
successful of these methods are naturally discussed at greatest
length, and an added note gives advice about the most suitable methods for individual cases, fine purification, and the
manipulation of the acridines. The next few chapters are
devoted to special properties, such as surface activity, dipole
moments, association and ionization, redox potentials, and
absorption, fluorescence, and phosphorescence spectra. The
relationship between the electron distribution and the physical and chemical properties of the compounds are discussed,
and reference is made to the possibility of prediction of the
properties of as yet unknown acridines.
Rodd’s Chemistry of Carbon Compounds. Edited by S.
Coffey. Vol. 1. Part D : Dihydric Alcohols, Their Oxidation Products and Derivatives. Elsevier Publishing Company, Amsterdam-London-New York 1965. 2nd Edit.,
xvi, 418 pages, 32 tables, bound Dfl. 65.-, subscription
DB. 55.-.
The largest section deals with the chemical properties of
acridine as well as of fused-ring and substituted acridines.
Special attention is given to the amino-substituted acridines,
with are used as medications and dyes A new feature of this
section is a short chapter o n the photochemistry of the acridines, which has recently been intensively studied. The photoproducts lead over to the acridanes, which are also discussed,
together with the hydroacridines, acridones, thioacridones,
and selenoacridones.
It is difficult to discern precisely for whom the dictionary is
intended. The vocabulary extends to practically all branches
of industrial technology (the list of subjects covered by the
dictionarly-contains over 90 entries). Translations of some
13000 terms are given, so that there is some justification for
the claim made in the foreword, that the user will seldom
be at a loss. However, even the author should not believe
that the user will never be at a loss, although he ofers this
a s a modest alternative to “seldom”.
H. Griinewald
The fourth part of the seven-part first volume of the 2nd
edition of Rodd (the 1st Edition[*] had only two parts) has
now been published, shortly after the appearance of the
earlier parts. Six well-arranged chapters deal with the preparation, properties, and reactions of acyclic compounds containing two functional groups (on different carbon atoms).
Six authors discuss the following classes of compounds:
glycols and glycol ethers, their sulfur analogues, nitro- and
amino-alcohols, diamines ( E . S. Waight); hydroxyaldehydes
and -ketones and dicarbonyl compounds (E. S. Waight);
monohydroxymonocarboxylic acids and their derivatives
( D . St. C. Black, G . M. Blackburn, 0.A . R, Johnston); amino
acids and their derivatives, peptides, hydrazo and azo acids
(1. E. Davies); keto acids ( D . St. C Black, G . M . Blackburn,
G . A . R . Johnston); dicarboxylid acids and their derivatives
(J. Oldham).
The chapters on keto acids, dicarboxylid acids, and amino
acids are much Iarger than in the first edition owing to the
rapid expansion of these fields. The arrangement of individual sections is on a mechanistic basis, e.g. the description of
diazo esters as nucleophilic and electrophilic reagents and as
carbene generators, or according to preparation, e.g. in the
preparation of peptides (by amino or carboxyl activation or
Like the first edition, the present edition contains an up-todate comparison of physical, chemical, and biological properties. In addition to the use of the acridines in clinical medicine. the-topics discussed include the interaction of these substances with nucleic acids and the relationship between their
physical and chemical properties and their bactericidal,
carcinogenic, and anticarcinogenic effects.
The final part of the book deals with the use of acridines as
pigments and dyes, corrosion inhibitors, biochemical reagents, fuel cells, and microscopic and photographic reagents. Numerous figures and tables make the book very
readable, and a great deal of information is presented in this
The fact that the present-day production of acridine-based
medications amounts to more than 500 tons per year testifies
to the considerable extension of the chemistry of acridine and
its derivatives. This is particularly clear from the new edition
of the book, which has not only organic chemists, but also
physical chemists as well as physicians and biologists as
potential readers. The book is strongly recommended to
anyone who wishes a survey of the present situation in this
V. Zanker
[NB 612 IE]
Angew. Chem. internat. Edit. 1 V d . 6 (1967)
1 No. 10
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physical, preparation, acridines, thein, properties, chemical, book, biological, uses, review
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