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Book Review The Chemistry of Indoles. Organic Chemistry a Series of Monographs Vol. 18. By R. J

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good ; Section 24, “Mechanical Separation of Liquids”,
which has reappeared in Volume 8, appears to the present
reviewer to be a step in this direction.
The overall arrangement of the volume, with sections on
Theory of Flow (Section I),
Rheology (Section 2), HighPressure Technology (Section 3) etc. on the one hand and
Flotation (Section 22), Mixing in the Viscous, Intrinsically
Viscous, Multiphase, Paste, Powder, and Granular States
(Section 26 b), etc. on the other shows how difficult it is to
achieve a logical division of the entire field. A search for
research results in a specific topic will often necessitate
reference to several sections of the book, and will often
reveal the presence of duplicate entries.
The collection of over 11000 literature references has been
assembled with much care. The note on abstracts of
certain of the references in the “Verfahrenstechnische
Berichte” is useful. Like its predecessors, this volume will
help many chemists and engineers to gain a general picture
of recent developments in the field of process technology;
it is only a pity that the high ofice will prevent many from
purchasing their personal copres
Hanns Hofmann
[NB 959 IE]
The Chemistry of Indoles. Organic Chemistry, a Series of
Monographs, Vol. 18. By R . J . Sundberg. Academic
Press, New York-London 1970. 1st ed., x, 489 pp.,
E 11.45.
The book provides a 500 page review of the advances
made in indole chemistry between about 1950 and 1969,
with reference to 1357 publications.
The author has made an excellent job of dividing up the
great volume of subject matter and making the book readable and interesting. The main aspects of indole chemistry
are presented in ten chapters containing many formulas
and reaction schemes. The chapters deal with: 1. Electrophilic Substitutions on the Indole Ring; 2. General Reactions of Substituted Indoles; 3. Synthesis of the Indole
Ring; 4. Synthesis of Special Indole Derivatives; 5. Oxidation, Degradation, and Metabolism of the Indole Ring;
6. Rearrangements, Ring Expansion, and Ring Opening
Reactions of the Indoles; 7. Hydroxyindoles and their
Derivatives; 8. Aminoindoles; 9. Ketones, Aldehydes,
and Carboxylic Acids Derived from Indole; 10. Naturally
Occurring Derivatives of Indole and the Indolines, and
their Physiological and Medical Importance.
The first few chapters are divided according to mechanism,
and an excellent idea of the reactivity of the indole ring is
therefore gained from many examples. Where possible,
the reactions found for indole are compared with those of
other groups of substances. The presentation is assisted
by a large number of tables.
The author places great value on the clarification of every
reaction, and he is critical of any results that seem uncertain
to him. Syntheses are placed in the forefront of the discussion.
It was obviously necessary to limit the discussion of indole
alkaloids, their synthesis, and their biosynthesis. Preference
has been given here to reactions that take place on the
indole ring itself.
The author has succeeded in abstracting all the essentials
from a subject matter that has now grown almost beyond
comprehension.
The reviewer considers the book to be particularly successful, and recommends it to all chemists who are concerned
Angew. Chem. internat. Edit. Vol. 10 (1971) 1 No. 5
with indoles, as well as to all libraries in the field. The book
is essential to everyone whose work involves the synthesis
of indoles.
Hans Plieninger [NB 956 IE]
Comprehensive Biochemistry. Edited by M . Florkin and E.
H . Stotz. Vol. 18: Lipid Metabolism. Elsevier Publishing
Company, Amsterdam-London-New York 1970. 1st
edit., xv, 398 pp., numerous figures, bound Dfl. 75.-.
Lipids, once neglected by biochemists because of their
complex behavior and analytical difficulties, are nowadays
at the center of interest on account of their important
role in the structure and function of biological membranes.
Their metabolism is the preparatory stage for these
physiological tasks. In animals this begins with resorption
after the ingestion of food, mobilization of free fatty
acids from the depots, and transport of the triglycerides
in the plasma, leading via biosynthesis in the liver and
other organs, especially nerve tissue, to breakdown by
f!-oxidation. In addition to this, bacteria and plants have
their own individual lipid metabolism.
The chapters and compilations of this volume of “Comprehensive Biochemistry””’, which roughly follow the
scheme set down are once more written by competent
authors practised in the art of writing surveys. The coordination of the chapters is somewhat careless, so that a
number of repetitions and overlaps occur, and some
authors use different nomenclature. However, the efforts
made by the editors to obtain the necessary degree of cooperation from the authors should not be underestimated :
an apologetic and reproachful note reveals that delays by
a few of the authors-obviously overburdened by other
literary duties-had a deleterious effect not only on the
completion but also on the unity of the volume. This
explains the gaps in the book, namely the lack of chapters
on fat synthesis in higher organisms, fatty acid oxidation,
steroid metabolism and end oxidation. The latter had
already been moved from Vol. 17 to Vol. 18 for the same
reason, and it is now intended to produce a special volume,
which will not make the handbook, already expensive in
itself, any cheaper. In the chapters offered, however, the
metabolism of simple and complex lipids is very comprehensively, but critically covered and fairly selectively
documented up to 1968. The length of the sections is not
always in accordance with the biological importance of
the material, but all contain a great deal of information so
that the volume deserves a plade at the side of the others.
L. Jaenicke
[NB 926 IE]
[*] Cf. Angew. Chem. internat. Edit. 8,995 (1969).
Chemistry through the Language Barrier. By E. Emmett
Reid. Johns Hopkins Press, Baltimore-London 1970.
1st ed., xi, 138 pp., boundE4.15.
In this book, which has the subtitle “How to scan
chemical articles in foreign languages with emphasis on
Russian and Japanese”, it is the author’s aim to pass on
his technique for reading information from foreignlanguage publications without learning the language.
Since only 55.9% of all publications are written in English,
the English-speaking chemist must encounter a large
number of articles that are not in English.
The author builds up his method for the understanding
of foreign-language publications, particularly the experimental part, from the assumptions that numbers, chemical
formulas and equations, and names of compounds are the
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