close

Вход

Забыли?

вход по аккаунту

?

Book Review Ullmans Encyclopdie der technischen Chemie. Edited by E. Bartholom E. Biekert H. Hellmann H. Ley (deceased) W. M. Wiegert (deceased) and E

код для вставкиСкачать
Table I . Acyl cyanides 2 from acyl iodides 1 and CuCN.
2,
R
a n-C,H,,
b
Ibl
c PhCH=CH
d (CH2)?CH
e PhCH:
Method
Yield
B
78
B
A
B
51
85 Icl
70
53
59 141
B
A
B
A
27
61
49
61
[90]
[a]
Ref. Yield
[%I
82 [Icl
38
in one batch. After being refluxed for 1-2 h, the mixture
was filtered from Cut, and CH2CI2was removed at 0-5 "C.
Kugelrohr distillation gave 2d (420 mg, 62%)l4].
Method B: 2e: A suspension of CuCN (1.2 g, 13 mmol)
in anhydrous acetonitrile (100 mL) was warmed to 4060°C and le"' (2.5 g, 10 mmol) was added in one batch:
after 2-3 min a yellow, almost clear solution resulted. The
solution was stirred for I h, and the acetonitrile was removed using a rotary evaporator. The product was dissolved in CHzCIzand Cul filtered off. After evaporation of
CH2C12 the residue was distilled twice (Kugelrohr, b. p.
100-120°C/3 torr) giving pure 2e (730 mg, 50%)[51.
[a] Yields were not optimized. [b] 2,7-Dioxo-octanedinitrile. [cl Crude yield;
F. Asinger, A. Saus, H. Offermanns, H. D. Hahn, Jusrus Liebigs Ann. Cbem.
691 (1966) 92.
Received: June 9, 1981
supplemented: December 2, 1981 [Z 961 b I€]
German version: Angew. Cbem. 94 (1982) 80
prepared by the convential procedure["'. Similarly, a,p-unsaturated acyl cyanides such as 3,4-dimethyI-2-oxo-3-pentenenitrile have been obtainedf3];hereby, the olefinic double bond tends to shift out of conjugation under more forcing conditions.
Acyl cyanides 2 can also be rapidly prepared under mild
conditions in a one-pot procedure starting from acyl chlorides, CuCN, and iodide ion"'.
Experimenlal Procedure
All reactions are carried out under an atmosphere of N2,
because acyl iodides 1 (X = I) are easily oxidized.
Method A : 2d: CuCN (1.2 g, 13 mmol) was gently refluxed in CH2CI2(I5 mL) and Id (1.4 g, 7. I mmol) added
[ I ] a) S. Hiinig, Angew. Cbem. 94 (1982) I ; Angew. Cbem. lni. Ed. Engl. 21
(1982) 36; J. Thesing, D. Witzel, A. Brehm, Angew. Cbem. 6 8 (1956) 425;
P. Kurtz in Houben-Weyl: Meiboden der Urgonircben Chemie. Vol. 8,
Thieme. Stuttgart 1952, p. 304: b) K. Findeisen, DOS 2614240, 2614242
(1977): K. Findeisen, H. Schwarz, DOS2614241 (1977); K. Findeisen. W.
Draber, H. Schwarz, DOS 252821 I (1977): K. Findeisen. K. H. Linker,
DOS 2820575 (1979), Bayer AG; c) H. Klenk, H. Offermanns, W.
Schwarze, DOS 2708 182, 2708 183 (1978), Degussa.
121 H. M. R. Hoffmann, K. Haase, Synthesis 1981. 715.
[3] K. Haase, A. Weber, unpublished results.
14) E. Zbiral, L. Fenz, Monaish. Cbem. 96 (1965) 1983.
IS] 2e: IR (CCI,) 2220 (m), 1720 (vs). 1495 (m), 1455 (m), 1210 (m).1055 (s),
715 1s) cm '_ ' H - N M R (60 MHz, CDCI,) 6=4.0 (s, 2H), 7.3-7.5 (m,
5H). "C-NMR (CDCI,) 6=50.8 (C-3), 113.1 (C-I), 128.6, 129.1, 129.2,
130.0 (aromat.), 174.4 (C-2).
BOOK R E V I E W S
Nucleotide Analogs. Synthesis and Biological Function. By
K . H. Scheit. John Wiley & Sons, New York 1980. xi,
288 pp., price E 16.00.
The importance of nucleotides in biological processes
has led to intense preoccupation with this class of natural
substances. The base, sugar and phosphate portions are
modified for a variety of purposes. One reason for the synthesis of nucleotide analogs is doubtless to use them in obtaining information about nucleotide metabolism and
about the expression and replication of genetic information. Another driving force is the hope that once the mechanisms of expression and replication are known, nucleotide analogs may be designed for general use as chemotherapeutics, for example as interferon inducers or antiviral agents. A wealth of literature difficult to grasp other
than by a specialist has been devoted to this theme, which
has been studied for many years and is still growing today.
This book fills a gap in this respect, since apart from an introduction to the subject, it presents an up-to-date review
of the synthesis and properties of nucleotide analogs, taking into account the structure-function relationships. Nucleotides are described that are modified on or in the heterocycle, together with others with unusual N-glycosyl
bonds and altered sugar radicals. Moreover, the book gives
an account of the newer methods of synthesizing phosphate esters, nucleotide polyphosphates and nucleotides
with modified phosphate radicals. The final chapter deals
84
0 Verlog Chemie GmbH. 6940 Weinheim. 1982
with the synthesis of chemically reactive and photoreactive
derivatives, e . g . for use in affinity labeling and affinity
chromatography. Ample references at the end of each
chapter constitute an introduction to the primary literature. The many summary formula illustrations facilitate the
reading of the text. Thus, a study of this book should be
profitable both for those new to the field and for those
who have been involved in it for years. For the first of
these, it is a modern introduction, and for the latter, an upto-date summary from which they should certainly derive
stimulus for their own research.
Hubert Koster [NB 553 IE]
Ullmanns Encyklopadie der technischen Chemie. Edited by
E. Bartholomh, E. Biekerl, H . Hellmann, H . Ley (deceased), w. M . Wiegert (deceased), and E. Weise. Vol.
19: Polyacryl-Verbindungen bis Quecksilber. Verlag
Chemie, Weinheim 1980. 4th Edition, xvi, 672 pp.,
bound, DM 525.00.
This 19th volume of Ullmann's Encyclopedia"] deals
mostly with the polymers, which occupy over half of the
volume; if the biopolymers are included (proteins with 67
pp., and polysaccharides, with 31 pp.), this rises to two'*'
See Angew. Cbem. 92 (1980) 866; Angew. Cbem. Inr. Ed. Engl. 19 (1980)
838.
0570-0833/82/0101-0084 $ 02.50/0
Angew. Cbem. in[. Ed. Engl. 21 (1982) No. I
thirds. There are two other classes of biopolymers, namely
cellulose and starches, that are not only dealt with in this
volume, but appear as cross-references to other volumes.
Further articles in this volume relate to organic intermediate products (e.g . Propanediol, 8 pp.; Propionic acid
and its derivatives, 9 pp.; Propylene, 8 pp.; Propylene oxide, I 1 pp. ; Propanol, 9 pp. ; Propanolamine, 1 1 pp.; Pyridine and its derivatives, 27 pp.), to pharmaceuticals and
their pre-products (Prostaglandins, 8 pp.; Purine and its
derivatives, 5 pp.; Pyrazolone, 8 pp.; Pyrimidine and its
derivatives, 3 pp.), to inorganic chemistry (Mercury, 29
pp.; Porcelain, 20 pp.), and to applied technologies (Pelleting compounds, 14 pp.; Powder metallurgy, 14 pp.; Pyrotechnics, 16 pp.). Of the polymers themselves, the polyolefins take up the most space with 60 pp., corresponding to
their importance, followed by the polyurethanes with 41
pp., polystyrene including its copolymers with 3 1 pp., polyacrylates and polymethacrylates with 30 pp., and finally
the polyesters with 28 pp. Under these entries for the individual classes of polymers, essentially only the manufacture and the chemical properties are dealt with, while anything to do with the application of the polymers is to be
found under other entries, mainly in Volume 15 under
Plastics or under special entries, for example Fibers, in
which, inter alia, the application of polyesters as chemical
fibers is dealt with. Special mention should also be made
of the entry on Polymerization techniques (59 pp.), which
gives a summary treatment of polymerization processes
such as solution, suspension and emulsion polymerization.
This review of an aspect of the technical production of polymers that is becoming increasingly important, fills a
long-standing gap in this area, and raises the question
whether it might not be worthwhile to expand this entry, in
due course, into a monograph. It should also be mentioned
that the entry on Proteins also gives an account of modern
methods for the biotechnological preparation of individual
proteins on the basis of unconventional carbon sources
(ethanol, alkanes). Finally, it only remains to be said that
this volume maintains the familiar high quality of UIImann's Encyclopedia, which should be available in any
chemical library on account of its information content.
Ulj-ert Onken [NB 555 IE]
Water Pollution Research and Development. Part 1-4. Executive Editor: S. H . Jenkins. Pergamon Press, New
York 1981. xii, 1388 pp., bound, $ 195.00.-lSBN 0-08026025-X
Two-phase Flows in Chemical Engineering. By D . Azbel.
Cambridge University Press, Cambridge 198 1. xx, 3 1 1
pp., bound, f 45.00.- ISBN 0-521-23772-6
Bindung und Struktur. Schiilerheft und Losungsheft. By M .
Tausch. Verlag Ferdinand Schoningh, Paderborn I98 1.
Schulerheft: 143 pp., bound, DM 14.20; Losungsheft: 18
pp., bound, DM 2.80.--ISBN 3-506-13901-0 bzw. 3-50613902-9
Analytikum-Methoden der analytischen Chemie und ihre
theoretischen Grundlagen. By K . Doerffel and R . Ceyer.
V E B Deutscher Verlag fur Grundstoffindustrie, Leipzig
1981. 5th Edit. 615 pp., bound, DM 60.00
Carl Duisberg. Eine Biographie. By H.-J. Flechtner. Econ
Verlag, Diisseldorf 1981. 432 pp., bound, DM 12.80.ISBN 3-430-12809-9
Advances in Polymer Science. Vol. 40. Luminescence. With
contributions by E. V. Anufrieva, K . P. Ghiggino. Yu. Ya.
Gotlib, D . Phillips. and A . J. Roberts. Springer-Verlag,
Berlin 1981. v, 174 pp., bound, DM 82.00.--ISBN 3-54010550-6
NMR. Vol. 19. NMR in Medicine. Edited by R . Damadian.
Springer-Verlag, Berlin 1981. v, 174 pp., bound, DM
98.00.-lSBN 3-540- 10460-7
Catalysis-Science and Technology. Vol. 1. Edited by J . R .
Anderson and M . Boudart. Springer-Verlag, Berlin I98 I .
x, 309 pp., bound, DM 142.00.-lSBN 3-540-10353-8
Lagerstatten der Steine, Erden und Industriemineralien.
Untersuchung und Bewertung (Vademecum 2). Published under the auspices of Gesellschaft Deutscher Metallhutten- und Bergleute (GDMB). Verlag Chemie,
Weinheim 1981. xii, 248 pp., bound, DM 69.00.--iSBN
3-527-25923-6
Catalysis and Chemical Processes. Edited by R. Pearce and
W . R . Patterson. The Blackie Publishing Group, Glasgow 1981. xix, 348 pp., bound, E 25.00.-1SBN 0-24944 160-8
Atmospheric Aerosol: Source/Air Quality Relationships.
ACS Symposium Series No. 167. Edited by E. S. Macias
and f. K . Hopke. American Chemical Society, Washington 1981. 359 pp., bound, $ 39.75.--ISBN 0-8412-06465
The Flavobacterium-Cytophaga Group. Edited by H . Reichenbach and 0. B. Weeks. GBF Monograph Series, No.
5. Verlag Chemie, Weinheim 1981. xiii, 217 pp., bound,
DM SS.OO.-lSBN 3-527-25919-8
13. Spektrometertagung. Dusseldorf, 29. 9. through I. 10.
1980. Edited by K.-H. Koch and H . Massmann. Walter
de Gruyter, Berlin 1981. xvi, 426 pp., bound, DM
140.00.- ISBN 3- 1 1-008456-2
Transition Metal Chemistry. Current Problems of General,
Biological and Catalytical Relevance. Edited by A .
Miiiler and E. Diemann. Verlag Chemie, Weinheim 198I .
xii, 338 pp., bound, DM SS.OO.-ISBN 3-527-25910-4
Reaktionen und Synthesen im organisch-chemischen Praktikum. By L.-F. Tietze and T. Eicher. Thieme Verlag, Stuttgart 1981. xxxii, 592 pp., bound, DM 54.00.-1SBN 3-13612301-8
Angew. Chem. In!. Ed. Engl. 21 (1982) No. I
85
Die Zelle. Struktur und Funktion. Edited by H. Metzner.
Wissenschaftliche Verlagsgesellschaft, Stuttgart 1980.
3rd completely revised edition. x, 612 pp., bound, DM
96.00.- ISBN 3-8047-0607-X
Emulsion Polymers and Emulsion Polymerization. ACS
Symposium Series No. 165. Edited by D.R. Bassett and
A. E. Harnielec. American Chemical Society, Washington 1981. 605 pp., bound, $ 49.75.-ISBN 0-8412-06427
L
Insights into Chemical Engineering. (Selected Papers of P.
V. Danckwerts). By P. V. Danckwerts. Pergamon Press,
New York 1981. xviii, 307 pp., bound, $65.00.--ISBN 008-026250-3
The Peptides. Analysis, Synthesis, Biology. Vol. 4. Modern
Techniques of Conformational, Structural, and Configurational Analysis. Edited by E. Gross and J. Meienhofer.
Academic Press, New York 1981. xix, 309 pp., bound, $
5 1.50.- ISBN 0-12-304204-6
Steroid Analysis by HPLC. Recent Applications. Vol. 16.
Edited by M. f. Kautsky. Marcel Dekker, Basel 1981.
xii, 397 pp., bound, SFr. 135.00.--ISBN 0-8247-1324-9
Hummel/Scholl. Atlas der Polymer- und Kunststoffanalyse.
Band 3: Zusatzstoffe und Verarbeitungshilfsmittel. By F.
Scholl. Carl Hanser Verlag, Munchen and Verlag Chemie, Weinheim 1981. 2nd completely revised edition.
xxiv, 696 pp., 1355 spectra bound, DM 520.00 (subscription price when ordering all volumes DM 450.00).ISBN 3-446-12564-7 bzw. ISBN 3-527-25799-3
Lehmerk Chemie-Einfiihrung in die Laboratoriumspraxis.
Arbeitsbuch 0. Von einem Autorenkollektiv.. VEB
Deutscher Verlag fur Grundstoffindustrie, Leipzig 198I.
2nd edit. 296 pp., bound, ca. DM 30.00
Quantum Mechanics. By H. F. Harneka. Wiley-lnterscience, Chichester 1981. xii, 387 pp., bound, f 24.00.ISBN 0-47 1-09223-1
Ion-Selective Electrode Reviews. Vol. 2. Edited by J. D. R.
Thomas. Pergamon Press, New York 1981. v, 261 pp.,
bound, $ 56.00.-lSBN 0-08-028434-5
'"C-NMR Data for Organometallic Compounds. By B. F.
Mann and B. F. Taylor. Academic Press, New York
1981. viii, 326 pp., bound, $ 32.50.-lSBN 0-12-4691501
Lasers in Chemical Analysis. Edited by G. M. Hieftje, J. C.
Travis, and F. E. Lytle. The Humana Press, Clifton 198 I.
xiii, 3 10 pp.. bound, f 29.00.-ISBN 0-89603-027-X
Annual Reports in Medicinal Chemistry. Vol. 16. Edited by
H.-J. Hess. Academic Press, New York 1981. xi, 364 pp.,
bound, $ 27.50.- ISBN 0- 12-040516-4
Three Concepts of Time. By K. G. Denbigh. Springer-Verlag, Berlin 1981. viii, 180 pp., bound, DM 39.00.-ISBN
3-540- 10757-6
Biologie. Eine Vorlesungsreihe fur Mediziner und Naturwissenschaftler. Edited by D. Starck, K. Fiedler, P.
Harth, and J. Richter. Verlag Chemie, Weinheim 1981.
xxxi, 1 1 18 pp., bound, DM 88.00.-ISBN 3-527-258213
The "0-Exchange Method in Zeolite Chemistry. Synthesis,
Characterization and Dealumination of High Silica
Zeolites. By R. uon Ballmoos. Salle
Sauerlander,
Frankfurt 1981. viii, 235 pp.. bound, DM 45.00.-ISBN
3-7935-5523-2
+
Corrigendum
Verfahrenstechnik in Chemieberufen. Berufsschullehrbuch.
By R. Kalthofen. G. Eckert. V. Mede, and H. Thomas.
VEB Deutscher Verlag fur Grundstoffindustrie, Leipzig
1981. cu. DM 23.00.
The following corrections should be made to the short
communication entitled, "Di-tert-butylthia- and -selenadiphosphirane" by Marianne Baudler, Horst Suchomel, Gabriele Furstenberg, and Ulrike Schings, Angew. Chern. Int.
Ed. Engl. 20 (1981) 1044:
Vom Mythos der mathematischen Vernunft. By D. Spalt.
Wissenschaftliche Buchgesellschaft, Darmstadt 1981. v,
406 pp., bound, DM 42.00.- ISBN 3-534-08758-5
"
Liquid Chromatography of Polymers and Related Materials
111. Edited by J. Cazes. Marcel Dekker, Basel 1981. 312
pp., bound, SFr. 108.00.--ISBN 0-8247-1514-4
On p. 1045, left-hand column:
... (tB~P)~SiPh,['l(l
: I : I), ..."
in line 13 should read:
". . . (tBuP),SiPhzf"(l : 1. I) .. ."
On the same page, same column: ". ..; but tert-butyl
groups ..." in line 49 should read: "...; but the tert-butyl
groups . ..".
___
Reqisiered r m t w s . irodemwhs. pic. used
0Verlag Chemie GmbH,
it# ibis joiiriial,
0-6940 Weinheim, 1982
eucn a.iihosi specific indicaimi ihe,rq/. are )ioi 10 be cowsidered ro!proircied by law.
- Printed i n the
Federal Republic of Germany by Zechnersche Buchdruckerei. Speyer/Rhein.
A l l rights reserved (including those of translation into foreign languages). No part of this issue may be he reproduced in any form - by photoprint, microfilm, or any other means - nor transmitted or translated into a machine language without written permission from the publishers. Only single copies ofcontributions. or parts thereof. may be reproduced for personal use. Copies reproduced and used other than for private purposes in an industrial or commercial undertakingare subject to copyright and, In such cases, a copyright lee must be paid to the VG WORT, Abteilung
Wissenschaft. Coethestr. 49. 8000 Munchen 2, from whom conditions of payment can be obtained on request.
Valid for users in the USA: The appearance of the code at the bottom of the first page of 3n article in this journal (serial) indicates the copyright owner's consent that copies of the article may be
made lor personal or internal use. or for the personal or internal use of specific clients. This consent is given on the condition. however. that the copier pay the stated per-copy fee through the
Copyright Clearance Center. Inc.. lor copying beyond that permitted by Sections 107 or 108 of the U.S. Copyright Law. This consent does not extend to other kinds of copying, such as copying
for general distribution. for advertising or promotional purposes. for creating new colleciive works. or for resale. For copying from back volumes of this journal see 'Permissions to Photo-Copy:
Publisher's Fee List' 01 the CCC.
Editorial office: Pappelallee 3. D-6940 Weinheim. Federal Republic ofGermany. Telephone (06201) 602-1. Telex 465S16 vchwh d.
Editor: 0. S w - d a r , Translation Editors: 1. G. Neil and A Siimm,,.
Publishers: Verlag Chemie GmbH. (Managing Director Dr. Helmai Giiiiiewald) Pappelallee 3. D-6940 Weinheim. Federal Republic of Germany.
Correspondence concerning advertisements should be addressed l o Verlag Chemie. GmbH. (Advertising Manager H . Boil,). Pappelallee 3. PO. Box 1260/1280, D-6940 Weinheim. Federal Republic al Germany, Telephone Weinheim (06201) 602-1. Telex 465516 vchwh d.
86
Angew. Chem. Int. Ed. Engl. 21 (1982) No. I
Документ
Категория
Без категории
Просмотров
2
Размер файла
406 Кб
Теги
wiegert, hellman, der, ullmans, deceased, encyclopdie, biekert, bartholom, book, technischen, chemie, edited, review, ley
1/--страниц
Пожаловаться на содержимое документа