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Book Review Vanadium. Toxicology and Biological Significance. By T. G. Faulkner-Hudson. Elsevier Monographs on Toxic Agents. Edited by E. Browning

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Vanadium. Toxicology and Biological Significance. By T. G .
Faulkner-Hudson. Elsevier Monographs o n Toxic Agents.
Edited by E. Browning. Elsevier Publishing Co., Amster140 pp.,
dam-London-New York 1964. 1st edit., X
11 figs., 6 tables, linen D M 19.50 (about $ 3.90).
This small work by a medical advisor in the British vanadiumprocessing industry will be greeted by all engaged with the
functions of vanadium as a trace element or with vanadium
poisoning. Topics dealt with include 1. the occurrence in
soils, plants, animals, and humans; 2. all the effects of V
known so far o n metabolism processes (sulfur, cholesterol,
lipid, and calcium metabolism, serotonin oxidation, and
hemopoesis); 3. questions of vanadium resorption, distribution in the organism, and excretion; 4. experimental
production of vanadium poisoning, toxicity phenomena
observed in industry, and the pertinent therapy and precautions. Descriptions which go beyond the limits suggested
by the title of the book are given of the mineral sources and
industrial extraction of the metal and of its compounds and
their technical uses. Tables are also given of the world
production and export figures for various countries. On the
other hand, the chemical properties of vanadium, e . g . its
great tendency to form complexes, which are undoubtedly
important for its biological effects, receive insufficient
attention. Although all details cannot be included in view of
the broad spectrum of aspects considered, brevity can be no
excuse for impreciseness. In addition to incorrect structural
formulae (e. g . coenzyme A, lipothiamide, p. 25), the work of
Lynen and Btoch is overlooked in the section on the biosynthesis of isoprenoids. a Cs intermediate of unknown structure in the isoprene series appears as a metabolite of mevalonic
acid, etc. The latest publications on the specificity of the vanadium uptake by marine invertebrates (tunicates) are not
mentioned, although the situation here is probably interesting
as a model for that in vertebrates as well. Otherwise the
literature is evaluated until 1961.The book can be recommended only to critical readers, but offers these many incentives.
H.-J. Bielig and W. Riidiger
[NB 3661224 IE]
Registered names, trademarks, etc. used in this journal, even without specific indication thereof, are not t o be considered unprotected by law.
0 1965 by Verlag Chemie, GmbH. - Printed in Germany by Druckerei Winter, Heidelherg.
All rights reserved. No part of this journal may be reproduced in any form whatsoever, e . g . by photoprint, microfilm, o r any other means. without
written permission from the publishers.
Editorial Office: Ziegelhauser Landstrasse 35, Heidelherg, Germany, Telephone 24975, Telex 461 855 kemia d, Cable address: Chemieredaktion
Chief Editor: W . Foerst . Editor: H . Griinewald.
Publishers: Verlag Chemie GmbH. (President Eduard Kreuzhage), Pappelallee 3 , Weinheim/Bergstr., Germany, and Academic Press Inc. (President
Walter J. Johnson), 1 1 1 Fifth Avenue, New York 3, N.Y., U.S.A., and BerkeIey Square House, Berkeley Square, London, W. 1, England.
Correspondence concerning advertisements should by addressed toVerlag Chemie, GmbH. (Advertising Manager W.Thiel), Pappelallee 3, WeinheimBergstr., Germany, Telephone Weinheirn 3635, Telex 46 55 16 vchwh. Cable address: Chemieverlag Weinheimbergstr.
Angew. Chem. internat. Edit. VoI. 4 (1965) / No. 9
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biological, toxic, significance, browning, book, faulkner, toxicology, agenti, hudson, edited, elsevier, review, vanadium, monograph
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