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Cover Picture Competitive Binding Assays Made Easy with a Native Marker and Mass Spectrometric Quantification (Angew. Chem. Int. Ed. 422003)

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Cover Picture
Georg Hfner and Klaus Theodor Wanner*
Mass spectrometric methods are on the march in competitive binding studies. In
pharmacological research these studies are widely used to characterize ligand–target
interactions. However, they usually require the use of radioligands. Now, with the aid
of mass spectrometry, it is possible to use native markers instead of radioligands. This
method and its use in a binding study on dopamine D1-receptors are described in the
Communication by G. Höfner and K. T. Wanner on page 5235 ff.
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market, 422003, native, competition, spectrometry, assays, int, mass, cover, angel, chem, made, quantification, easy, picture, binding
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