Cover Picture Enantioselective Catalysis and Analysis on a Chip (Angew. Chem. Int. Ed. 152006)код для вставкиСкачать
Cover Picture Detlev Belder,* Martin Ludwig, Li-Wen Wang, and Manfred T. Reetz* Synthesis and analysis on a chip are possible with the microfluidic system shown (a two-Euro coin is shown for scale). D. Belder, M. T. Reetz et al. show in their Communication on page 2463 ff. how this chip is used to test enantioselective biocatalysts created by directed evolution. The model system used is the hydrolitic kinetic resolution of chiral glycidyl phenyl ether with different epoxide hydrolase mutants. Aided by integrated electrophoreses, chiral separation of the products is possible within 80 s. Solar Cells In the Minireview on page 2338 ff., N. Robertson discusses the optimization of dye molecules for sensitized solar cells. Careful design of the dye can minimize energyloss mechanisms and increase the efficiency of solar-to-electrical energy conversion. Bioorganic Chemistry In their Review on page 2348 ff., L. L. Kiessling et al. describe the advantages of using synthetic multivalent ligands for studies on protein complexes. Directed ortho-Metalation A precomplex formed from an aromatic amide, an alkali metal, and zinc that directs ortho-zincation is described by R. E. Mulvey et al. in their Communication on page 2370 ff.