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Cover Picture Manufacturing Immunity to Disease in a Test Tube The Magic Bullet Realized (Angew. Chem. Int. Ed. 482006)

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Cover Picture
Richard A. Lerner*
In Paul Ehrlichs era selecting an antibody for a specific target was a physical
process, involving live animals. R. A. Lerner shows in his Review on page 8106 ff. how
combinatorial libraries are the incarnation of Ehrlichs (see inset in the cover picture
showing “Der B%cherwurm” by Carl Spitzweg) “magic bullet”, proposed more than
100 years ago, and nowadays hundreds of millions of different antibodies can be
provided in a couple of hundred microliters of solution in a test tube.
Hollow Nanostructures
Dendritic platinum nanosheets grow and link together within a liposomal bilayer to
form spherical hollow nanocages. J. A. Shelnutt and co-workers describe this method
in their Communication on page 8126 ff.
Fluorinated Phthalocyanines
The unique photosensitivity of monomeric trifluoroethoxy-substituted zinc
phthalocyanines conjugated with deoxyribonucleosides is described in the
Communication by N. Shibata, T. Toru, and co-workers on page 8163 ff.
Molecular Recognition
G.-T. Li and co-workers describe in their Communication on page 8145 ff. a combined
molecular imprinting and colloidal crystal approach to prepare ordered 3D
macroporous photonic polymer films for specific enantiomer recognition.
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