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Cover Picture Soluble Synthetic Analogues of Malaria Pigment Structure of Mesohematin Anhydride and its Interaction with Chloroquine in Solution (Angew. Chem. Int. Ed. 272011)

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D 3461
www.angewandte.org
2011–50/27
Acyl Transfer
P. R. Schreiner and C. E. Müller
Catalytic Hydrosilylation
M. Beller et al.
Quaternary Carbon Centers
M. Shimizu
Coordination Polymers
A. Facchetti
ACIEFS 50 (27) 5973–6182 (2011) · ISSN 1433–7851 · Vol. 50 · No. 27
Cover Picture
D. Scott Bohle,* Erin L. Dodd, Aaron J. Kosar, Lauren Sharma,
Peter W. Stephens,* Liliana Surez, and Dagobert Tazoo
Transmission, invasion, digestion, crystallization, and reproduction are all critical
parts of the life cycle of the malaria parasite. With the onset of drug-resistant strains,
new antimalarial drugs are urgently needed, and all aspects of the parasites unique
lifecycle and biochemistry need to be exploited. D. S. Bohle, P. W. Stephens, et al.
describe in their Communication on page 6151 ff. new soluble malaria pigment
derivatives and characterize their interactions with the quinoline antimalarials.
Acyl Transfer
P. R. Schreiner and C. E. Mller describe in their Review on page 6012 ff. classes of
organocatalysts for the efficient electroselective transfer of acyl groups onto
nucleophiles for the preparation of chiral compounds. Many of these reactions can
compete with enzyme- and metal-catalyzed variants.
Crystal Growth
In their Communication on page 6044 ff., Z. Zhang, S. Wang, et al. report the
controlled synthesis of water-soluble single crystals of NaCl and KCl with complex
hopper-like nanoarchitectures that grow at the interface between water droplets and
organic solvent.
Biomimicry
Living yeast cells can be individually encapsulated within thiol-functionalized silica
shells. In their Communication on page 6115 ff., I. S. Choi and co-workers report
how the shells can be further functionalized in various coupling reactions.
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mesohematin, 272011, analogues, synthetic, anhydride, chloroquine, int, solutions, cover, structure, angel, malaria, pigment, chem, interactiv, soluble, picture
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