вход по аккаунту


Honorary Doctorate for H.2Brunner C. T. Walsh Receives Boehringer Ingelheim Award

код для вставкиСкачать
Angewandte Chemie[1] and of a popular
book on chirality: “Rechts oder links—
In der Natur und anderswo” (WileyVCH, 1999).
Photo: Uli Benz
C. T. Walsh Receives Boehringer
Ingelheim Award
Honorary Doctorate for H.
The chemistry department of the Technische Universitt Mnchen (Germany) has
awarded Henri Brunner of the Universitt
(Germany) an honorary
doctorate. This distinction was awarded
in recognition of “his trend-setting
research in organometallic chemistry
and homogeneous catalysis, with which
he has paved the way to modern enantioselective methods for the preparation
of chiral fine chemicals and precursors
to pharmaceutically active compounds”.
Brunner completed his PhD in 1963
at the Universitt Mnchen under the
guidance of E. O. Fischer (Nobel Prize
in Chemistry, 1973). After a postdoctoral year at the University of California, Los Angeles in the research group
of H. D. Kaesz, he returned to Mnchen, where he completed his habilitation in 1969. In 1971 he accepted the
chair for inorganic chemistry at the Universitt Regensburg, which he held until
he received emeritus status in 2004. He
has been awarded many prizes for his
work, including the Carl Duisberg
Memorial Award of the Gesellschaft
Deutscher Chemiker (German Chemical Society, GDCh) in 1970, the Horst
Pracejus Award of the GDCh in 1999,
and the Humboldt Research Award for
German–French Cooperation in 1993.
Brunner was a member of the Editorial
Board of Angewandte Chemie from
1989 to 1997 (Chairman 1993–97). He
is the author of three Reviews on asymmetric transition-metal catalysis in
Angew. Chem. Int. Ed. 2004, 43, 4687
Christopher T. Walsh
majored in biology
at Harvard College
USA) and completed
his PhD in the
research group of
Fritz Lipmann at
The Rockefeller University in New York.
He carried out postdoctoral research
from 1970 to 1972 with R. H. Abeles,
then took up a position at Massachusetts
Institute of Technology (MIT, Cambridge, USA) to study enzymatic reactions. Focal points of his research
included the design of inhibitors and
enzymatic catalysis of the Baeyer–Villiger oxidation.[2a] After 15 years he left
MIT to become Professor of Biological
Chemistry and Molecular Pharmacology at Harvard Medical School. There
he investigates enzymes of therapeutic
relevance and the mechanism of action
of antibiotics, such as vancomycin.[2b, c]
Walsh is the recipient of the Boehringer Ingelheim Award 2004 of the
Division of Chemical Toxicology of the
American Chemical Society (ACS) for
his work on the mechanism of action
of xenobiotic chemicals, in particular
antibiotics, in living organisms, and on
antibiotic resistance. Walsh is the
author of several books, including Antibiotics (ASM Press, 2003) and Enzymatic Reaction Mechanisms (Freeman,
1978). Walsh is a member of the Editorial Advisory Board of ChemBioChem.
[1] Most recently: H. Brunner, Angew.
Chem. 1999, 111, 1248; Angew. Chem.
Int. Ed. 1999, 38, 1194.
[2] a) C. T. Walsh, Y.-C. J. Chen, Angew.
Chem. 1988, 100, 342; Angew. Chem.
Int. Ed. Engl. 1988, 27, 333; b) C. T.
Walsh, ChemBioChem 2000, 1, 99;
c) B. K. Hubbard, C. T. Walsh, Angew.
Chem. 2003, 115, 752; Angew. Chem.
Int. Ed. 2003, 42, 730.
DOI: 10.1002/anie.200461702
Editorial Note: Diamond
Synthesis in Doubt
Last year in Angewandte Chemie and in
the Journal of the American Chemical
Society Quianwang Chen et al. reported
diamond syntheses from MgCO3-Na
and CO2-(Li, Na, K), respectively.[1, 2]
The authors have apologized for failing
to cross-reference the papers and for
manipulation of some of the data (see
the second paragraph in the Correspondence from Z. Lou and Q. Chen
on page 4700).
In addition, the results reported in
both publications are heavily criticized
by H. Sachdev in the Correspondence
on page 4696:[3] The details of the reaction conditions are not reported in sufficient detail for the work to be repeated
and the characterizations (or even
proof) of the final products are not without doubt; furthermore, the characterization of intermediate products, important for the postulated reaction mechanism, is missing. Even if a diamond synthesis is, in principle, possible under the
conditions presumably present in the
reaction system used by Chen et al.
then its actual realization remains
doubtful. Chen and Lou give a series
of arguments in their Reply[4] in order
to support their diamond synthesis, however, they close with the comment “we
could produce diamonds from time to
time in MgCO3-Na and CO2-(Li, Na,
K) system” (italicized by me), which
naturally casts doubts about the reproducibility. Hopefully this Note and the
two Correspondences[3, 4] will lead to a
rapid resolution of the problem of
whether or not diamonds can be prepared by the method of Chen et al.[1, 2]
Peter GLlitz
[1] Z. S. Lou, Q. W. Chen, W. Wang, Y. T.
Qian, Y. F. Zhang, Angew. Chem. 2003,
115, 4639; Angew. Chem. Int. Ed. 2003,
42, 4501.
[2] Z. S. Lou, Q. W. Chen, Y. F. Zhang, W.
Wang, Y. T. Qian, J. Am. Chem. Soc.
2003, 125, 9302.
[3] H. Sachdev, Angew. Chem. 2004, 116,
4800, Angew. Chem. Int. Ed. 2004, 43,
[4] Z. S. Lou, Q. W. Chen, Angew. Chem.
2004, 116, 4804, Angew. Chem. Int. Ed.
2004, 43, 4700.
2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Без категории
Размер файла
88 Кб
awards, honorary, ingelheim, walsh, 2brunner, receive, doctorate, boehringer
Пожаловаться на содержимое документа