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Inside Cover A Programmable DNA-Based Molecular Valve for Colloidal Mesoporous Silica (Angew. Chem. Int. Ed. 282010)

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.
Controlled
molecular valves …
… for sealed nanocontainers are of interest for targeted drug delivery and self-healing
polymers. In their Communication on page 4734 ff., T. Bein and co-workers present a
DNA-based valve system for colloidal silica that has a precisely programmable opening
temperature. This nanodevice consists of a mesoporous silica host, functionalization of
the pore mouths with a DNA linker, and biotin–avidin coupling for valve closure.
Inside Cover
Axel Schlossbauer, Simon Warncke, Philipp M. E. Gramlich,
Johann Kecht, Antonio Manetto, Thomas Carell, and Thomas Bein*
Controlled molecular valves for sealed nanocontainers are of interest for targeted
drug delivery and self-healing polymers. In their Communication on page 4734 ff., T.
Bein and co-workers present a DNA-based valve system for colloidal silica that has a
precisely programmable opening temperature. This nanodevice consists of a
mesoporous silica host, functionalization of the pore mouths with a DNA linker, and
biotin–avidin coupling for valve closure.
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colloidal, molecular, dna, base, int, cover, angel, mesoporous, 282010, chem, valves, programmable, insider, silica
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