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Inside Cover Multiplication of Human Natural Killer Cells by Nanosized Phosphonate-Capped Dendrimers (Angew. Chem. Int. Ed. 142007)

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Inside Cover
Laurent Griffe, Mary Poupot, Patrice Marchand, Alexandrine Maraval,
Cdric-Olivier Turrin, Olivier Rolland, Pascal Mtivier, Grard Bacquet,
Jean-Jacques Fourni, Anne-Marie Caminade,* Rmy Poupot,* and
Jean-Pierre Majoral*
Human peripheral blood mononuclear cells (white blood cells) cultured in the
presence of dendrimers capped with phosphonate groups reveal a selective
multiplication of natural killer (NK) cells. In their Communication on page 2523 ff.,
A.-M. Caminade, R. Poupot, J.-P. Majoral, and co-workers describe the synthesis of
various phosphazene dendrimers and their effect on NK cells, which play a key role in
anticancer immunity. The picture shows a fluorescence microscopy image of a NK cell
(red) engaged with target cancer cells (green).
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142007, nanosized, phosphonate, killer, dendrimer, multiplicative, human, capper, cells, int, cover, angel, chem, natural, insider
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