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Inside Cover Total Synthesis and Configurational Assignment of PasteurestinA and B (Angew. Chem. Int. Ed. 482007)

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Inside Cover
Marion Kgl, Lothar Brecker, Ralf Warrass, and Johann Mulzer*
Application in veterinary medicine was proposed for the sesquiterpenoids
pasteurestins A and B because of their strong and selective activity against Pasteurella
haemolytica. A Vollhardt [2�] cycloaddition was the key step in their total
synthesis, which is described by J. Mulzer et al. on page 9320 ff., and subsequently
their absolute and relative configurations could be established and their biological
activities more precisely specified. Another feature of the synthesis of pasteurestin B
is a tin(II) enolate mediated Reformatsky-type condensation.
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int, cover, angel, synthesis, tota, 482007, chem, configuration, pasteurestina, insider, assignments
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