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Epileptic syndromes in infancy childhood and adolescence ed 2. Edited by Joseph Roger Michelle Bureau Charlotte Dravet Fritz E. Dreifuss. Andr Perret and Peter Wolf London John Libbey 1992 418 pp illustrated $102

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which fills a long-unmet need in the field of cerebral metabolism by summarizing authoritatively a vast and rapidly expanding literature. This volume targets a broad readership,
including neuroscientists with a particular interest in cerebral
blood flow and metabolism, physiologists and pharmacologists, and cliniciansiinvestigators in neurology, neurosurgery,
and allied disciplines. The book is superbly illustrated, exhaustively referenced, and beautifully printed. It will be
broadly and enthusiastically welcomed by pre- and postdoctoral students, residents, and seasoned neuroscientists alike.
The authors are to be congratulated on their superb accomplishment.
Myron D. Ginsberg, M D
Advances in Neurology, Vol 60: Parkinson’s Disease.
From Basic Research to Treatment
Edited by Htrotaro Narabuyah, Toshzharu Nagatsu.
Nobuo Yanagisawa. and Yoshikuni Mizuno
New York, Ratan, 1993
773 pp, illustrated, 8150.00
This attractively produced book contains the proceedings of
the Tenth International Symposium on Parkinson’s Disease,
held in Tokyo in 1991. It contains 126 chapters dealing with
every major aspect of the subject, including basic work on
the basal ganglia, studies related to degenerative processes,
the molecular biology and various clinical aspects of the disease, drug therapy, and newer therapeutic approaches such
as transplantation procedures. The chapters vary considerably
in importance of subject matter, the extent of any general
review of the topic under discussion, and the style of presentation.
The volume would have been more complete if the editors
had included summaries of the different sections of the book,
with a critical analysis of the various contributions and, where
appropriate, a consensus of opinion concerning the major
issues that are covered. Despite this deficiency, the book
remains very comprehensive in its scope and detail and will
be of interest to neurologists concerned with the management of patients with Parkinson’s disease and to neuroscientists working in related fields.
Michael J. Aminoff;M D
Genetics and Neurology, ed 2
By Sarah Bundey
Edinburgh. Churchill Livingstone. 1992
459 pp, illustrated. $125.00
This excellent monograph has the audacity to cover the entire
range of hereditary neurological diseases in the space of 450
small pages. The author has succeeded in producing a very
readable and succinct book that provides much clinical information about all of the common genetic disorders and at least
a few lines about nearly all of the rare ones. The genetic
discussions emphasize clinically important subjects such as
prenatal diagnosis, detection of subclinical cases and carriers,
and differential diagnosis. This is a very practical book that
can serve as a first resource and as a guide to the more
specialized medical literature.
118 Annals of Neurology
Vol 34 No 1 July 1993
The field of molecular genetics is changing rapidly, and it is
not surprising that some new information about chromosome
localization or gene identification either was too recent to be
included or received only brief mention in a postscript. For
example, the trinucleotide repeat in myotonic muscular dystrophy and the chloride channel linkage in myotonia congenita are not mentioned. The fragile X syndrome, the next
most important hereditary cause of mental retardation after
Down’s syndrome, is mentioned only in a table, and the abnormal trinucleotide repeat in that disease is not discussed.
The discussion of the myotonias and periodic paralyses gives
little information about the altered membrane physiology in
those disorders, and although the linkage of hyperkalemic
periodic paralysis to the sodium channel gene on chromosome 17 is mentioned, the linkage of the same gene to paramytonia is not.
Despite these minor defects, this book is probably the
single best reference work on hereditary neurological diseases for general clinical use.
Robert B . Layzer. M D
Epileptic Syndromes in Infancy, Childhood and
Adolescence, ed 2
Edited by Joseph Roger, Michelle Bureau, Charlotte Dravet,
Fritz E. Dreifus, Andy6 Pewet, and Peter Wolf
London, John Libbey, 1992
41 8 pp, illustrated, $102.00
I was pleased to be asked to review this book because the
first edition, commonly referred to as the “Blue Bible” or
“Blue Guide” of epileptic syndromes in children is, by far,
the most commonly consulted book in my library. It was also
the book most frequently “borrowed” by our fellows and
The first edition, published in 1985, was based on a 1983
workshop and was an attempt to summarize current knowledge of the epileptic syndromes of children. Recommendations from this workshop were incorporated in the 1989 revised classification of the epilepsies, published in Epilepsia.
The second edition follows the same format as the first with
short, fact-filled chapters by a primarily European group of
authorities. Most of the chapters have been revised by their
original authors. Unfortunately, this was not the case for several important topics. D r Henri Gastaut, because of retirement, did not revise the chapter on epilepsy with occipital
paroxysms. As pointed out in an update by Roger and Bureau, it is now clear that the syndrome described by Gastaut
is much rarer than suggested originally. Likewise, much has
changed since Bancaud’s chapter on Ko jewnikow’s syndrome
and more than an update was required. In addition, little new
information is provided on some of the rarer syndromes such
as benign partial seizures of adolescence and benign partial
epilepsy with affective symptoms. The fact that these disorders have only been reported by a handful of authors questions their legitimacy as syndromes. O n the plus side are
several new additions, including an excellent review of progressive myoclonic epilepsy.
Unfortunately, many of the weaknesses of the first edition
persist in the second edition and could have been avoided
with tighter editing. There is a great deal of variability in the
writing style from chapter to chapter and there are many
awkward phrases and errors in syntax. The print is small and
many of the electroencephalograms are of marginal quality.
The annoying decision to include many one-sentence paragraphs coupled with the failure to indent paragraphs makes
for difficult reading. Inexplicably, the excellent summaries of
the critical components of the syndromes, included in the
first edition, are no longer included.
Should neurologists purchase this book? For the neurologist seeing large numbers of children with epilepsy, definitely
yes. Is the second edition better than the first? Somewhat.
Could it have been even better? Certainly. Will I use it as
much as the first edition? Absolutely!
Gregoty L. Holmes, M D
Carpal Tunnel Syndrome and Other Disorders of the
Median Nerve
By Ricbard B. Rosenbaum and Jose* L. Ocboa
Boston, Butteworth-Heinemam. 1993
358 pp, illustrated, $9S5.00
Carpal tunnel syndrome is one of the most important neurological syndromes. It has a high frequency in the population,
is a frequent reason for neurological consultation, and is very
responsive to treatment. Carpal tunnel syndrome is often in
the news as one of the best known occupational disorders.
The American Academy of Neurology and the American
Association of Electrodiagnostic Medicine have chosen carpal
tunnel syndrome as one of the early topics for establishment
of practice parameters. It is appropriate to have a book that
focuses primarily on this syndrome, collating most of the
world's literature and organizing knowledge in a logical and
comprehensive fashion.
All aspects of the syndrome are covered, from anatomy
and pathophysiology to clinical and laboratory assessment, to
medical and surgical treatment. In the review of epidemiology, many of the clinical series have been pooled to produce
a large data base. Particularly valuable is the discussion of
the thorny question of whether occupational activities really
produce the disorder. All views seem quite sensible.
The range of the book is wide and includes interesting
discussions about mechanisms of nerve injury, methods for
study of unmyelinated fibers, and reasons for radically revising the concept of reflex sympathetic dystrophy. It is a valuable book for all neurologists.
Mark Hallett, M D
Lumbar Disc Disease, Second Edition
Edited by Russell W. Hardy. J r
New York, Raven Press, 1993
362 pp, illustrated, $125.00
This multiauthored monograph covers the subject of lumbar
disc disease thoroughly and concisely. The extensively revised and expanded second edition includes the striking
changes in diagnosis and treatment that have occurred in
recent years with the rapid development of magnetic resonance imaging and new surgical techniques, including percutaneous and microdiscectomy. The 3 1 chapters cover epidemiology, clinical diagnosis, imaging, electrodiagnosis,
nonoperative treatment and manipulations, spinal fusion,
complications of surgery, lumbar stenosis, back pain in children, arachnoiditis, and medicolegal aspects of lumbar disc
disease. Controversial issues regarding management of lumbar disc disease are well aired although not always resolved.
The neurologist is often the conduit in referring patients to
neurosurgeons and orthopedic surgeons. This volume will
prove very valuable in keeping the clinical neurologist abreast
of the management of the commonplace, controversial, and
often vexing clinical problems associated with lumbar disc
disease. The book is well illustrated and referenced and
highly recommended for neurological residents and consultants.
Robert A. Fisbman, M D
Annals of Neurology
Vol 34
No 1 July 1993
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102, illustrated, 1992, john, dreifuss, dravet, charlotte, bureau, 418, peter, london, syndrome, andrã, michelle, childhood, libben, roger, wolf, epileptic, perret, infancy, adolescenta, edited, joseph, fritz
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