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Essentials of neurology Fifth edition By Sir John Walton Marshfield MA Pitman Publishing Inc. 1982 488 pp illmtrated $30

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the second is less useful, but does not detract from the overall
strength of this well-planned, inexpensive text.
Status Epilepticus: Mechanisms of Brain Damage
and Treatment
(Advances i n Neurology, Vol 34)
Edited by A. V. Delgado-Escueta, C . G. Wasterlain,
D. M . Treiman, and R . J . Porter
New York, Raven Press, 1983
This very fine volume reports the papers presented at an
international symposium in 1980. In fifty-seven chapters the
volume covers electroclinical correlation, mechanisms of
brain damage, and treatment. The quality is high, and the
authors are a well-chosen cross section of the outstanding
workers in this field worldwide. The symposium goes well
beyond the already available literature and can be highly recommended.
Fred Plum. M D
New York, NY
Essentials of Neurology, Fifth edition
By SirJohn Walton
Marshfield, M A , Pitman Publishing, Inc., 1982
488 pp, illmtrated, $30.95
This successful book, now in its fifth edition, is a descriptive
text, relatively free of charts, lists, and illustrations. The author intends it to be useful to undergraduates and postgraduates alike; he comes closest to satisfying the former.
The book is too wordy in style and too oversimplified to be
used as a reference.
The first eleven chapters, which outline the neurological
examination and describe various functional systems, are exceptionally well conceived and probably merit publication as
a separate volume. The review of the neurological examination is concise but probably would not be adequate for an
undergraduate as the sole guide to its performance. The
chapters reviewing motor and sensory systems are excellent;
each chapter gives essential anatomic and functional data that
permit the reader to understand the overall properties of the
system. In addition, the illustrations are of good quality and
are carefully chosen to reinforce the ideas stated within the
text. A minor criticism of this section is the lack of an
itemized description of the function of each cranial nerve.
The subsequent eight chapters, dealing with the various
categories of disease, are of uneven quality. Chapters devoted
to neoplasm, infection, and demyelinating disease are very
good, but might have been supplemented by appropriate
computed tomographic scans, considering their essential role
in the management of such cases. The other chapters are too
diffuse and scarcely mention differential diagnosis, pathogenesis, or specific disease characteristics. The final chapter
on therapy is cosmic in scope but overdetailed with lists of
substitute medications, and its separation from the disease
descriptions disrupts the overall continuity.
In sum, this volume encompasses two books. The first is
excellent and is heartily recommended to all undergraduates;
616 Annals of Neurology
Vol 15 N o 6 June 1984
H . Schaumburg, M D
Bronx, N Y
Neuroleptics: Neurochemical, Behavioral,
and Clinical Perspectives
Edited by Joseph T . Coyle and S . J . Enna
New York, Raoen Press, I983
331 pp, $55.00
This book provides a succinct and balanced survey of up-todate basic and clinical aspects of neuroleptic drugs. The chapters that discuss the use of neuroleptics for psychotic disorders (John Davis et al), the use of neuroleptics for neurologic
disorders (VanWoert), and the dopamine hypothesis for
schizophrenia (Pearlson and Coyle) are particularly absorbing
and scholarly discussions.
Since the index is rather incomplete, the value of this book
as a reference is limited. In the three chapters that discuss the
neurologic side effects of these drugs, there is no mention of
the neuroleptic malignant syndrome. Many readers will not
agree with statements such as “because of the lipid solubility
of neuroleptics, a large fraction of the drug is bound to
plasma proteins” or “the movements {of tardive dyskinesia)
are, in essence, identical to those seen in Huntington’s
chorea.” There is no discussion or editorial comment to resolve some of the different points of view held by different
authors (for example, the usefulness of monitoring plasma
levels in neuroleptic agents).
Despite these shortcomings, this book will be valuable for
neurologists and neuroscientists who have an interest in
neuropharmacology or movement disorders.
Linda A. Hershey, M D , PhD
Cleveland. OH
By G. M . Shepherd
New York, Oxford Unioersity Press, I983
Illustrated, $35.00
Shepherd’s Neurobiology is an introductory textbook that
“aims to summarize modern knowledge about nerve cells and
their organization into functional circuits, and show how this
relates to animal behavior.” As a book targeted for neuroscience newcomers, it achieves its goal.
The book is divided into four parts. An introductory section includes an overview of cellular neurobiology and comparative anatomy and physiology of vertebrates and invertebrates. The second part consists of an in-depth treatment of
cellular mechanisms, with chapters on neuron organization,
synaptic function, action, membrane, and synaptic potentials,
transmitters and modulators, and neural development. Parts
three and four are devoted to sensory and moror systems,
respectively, with chapters covering each sensory system, au-
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essential, publishing, 488, neurology, illmtrated, inc, john, edition, 1982, sir, pitman, fifty, walton, marshfield
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