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ajrccm-conference.2012.185.1 meetingabstracts.a2363

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A106 ADVANCES IN DIAGNOSIS AND TREATMENT OF PULMONARY EMBOLISM / Poster Discussion Session / Sunday, May
20/2:00 PM-4:30 PM / Room 2024 (West Building, Level 2), Moscone Center
Utility Of Prognostic Scale In The Identification Of Pulmonary Embolism With Fatal Outcome
J. de Miguel Diez1, J. Jareno Esteban2, M. Izquierdo3, A. Nieto4, C. Gutierrez5, L. Puente Maestu6, S. Alcolea Batres7, Group study
of pulmonary thromboembolism in Madrid
1Hospital Gregorio Marañón, Madrid, Spain, 2, 3Fundación Alcorcón, Madrid, Spain, 4Hospital Clínico San Carlos, Madrid, Spain, 5Hospital
Central de la Defensa, Madrid, Spain, 6Hospital Gregorio Maranon, Madrid, Spain, 7Hospital La Paz, Madrid, Spain
Introduction: Pulmonary embolism (PE) is a common disease. Mortality can reach up to 10% of cases according to series published in the
literature.
Objectives: To study, in patients with PE, clinical factors, comorbidity, prognostic scales, and treatment related to fatal outcome. Methods:
Patients diagnosed with PE were classified into two groups: a) faltal pulmonary thromboembolism; b) non-fatal pulmonary
thromboembolism. For prognostic evaluation we used PESI scale. We consider cases of PE associated with death those in which death
occurred from the time of diagnosis until 30 days later.
Results: The fatal outcome of pulmonary embolism accounted for 9% of patients in our series. Among patients with fatal PE, there were
not grade I or II of the PESI scale, being the most frequent grade V (46.2%). Among patients with non-fatal PE only 18% showed a grade V
on this scale, distributed the rest among the grade II (22.4%) to IV (28.4%) and only 2.6% in grade I. Patients with PE and cancer are 20.6
times more likely (95% CI 6 to 68) of exitus that non-cancer (p <0.001).
Conclusions: Patients with pulmonary embolism and fatal outcome have a scale PESI III, IV or V, and are associated with malignancy in 77%
of cases. The association of pulmonary thromboembolism and cancer increase the risk of death relative to patients with pulmonary
thromboembolism without cancer.
This abstract is funded by: None
Am J Respir Crit Care Med 185;2012:A2363
Internet address: www.atsjournals.org
Online Abstracts Issue
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