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book reviews
Haematology Case Studies with Blood Cell Morphology and
Pathophysiology
I. Singh, A. Weston & A. Kundur
Academic Press, London, 2017
This book approaches haematological cases from the point of
view of the laboratory scientist or haematologist, who is presented with a brief history, a full blood count and a blood
film. Each case is illustrated with an annotated photograph
of the blood film. This is a good educational approach as it
means that laboratory scientists and haematology trainees
can work out a differential diagnosis before reading the
denouement. The final diagnosis is followed by a discussion
of the pathophysiology of the condition portrayed. There are
61 cases in all with a satisfactory range of diagnoses. One
very puzzling defect, which does reduce the educational
value, is that the results of the blood count are given without
any information as to the age and gender of the patient,
making results sometimes hard to interpret. It would have
occasionally also been useful to have known the ethnic origin
of the patient. There are normal ranges tucked away at the
end of the book but as they are not in the Table of Contents
readers might not discover them till they reach the end. The
differential diagnoses can also be somewhat eccentric. This
book could be useful to biomedical scientists who wish to
expand their knowledge of the haematological disorders
discussed.
Barbara J. Bain
Department of Haematology, St Mary’s Hospital,
Praed Street, London, W2 1NY, UK
E-mail: b.bain@imperial.ac.uk
doi: 10.1111/bjh.14994
Neonatal Transfusion
D.A. Sesok-Pizzini (ed)
Springer, 2017
As the practice of haematology becomes more and more specialised, books such as this dealing with a single topic
become increasingly useful. The remit is slightly wider than
the title suggests since intrauterine transfusion is also considered. This is a useful addition since management of the fetus
and the neonate should be seen as a continuum. All of the
12 authors are from the USA so that practices described are
sometimes different from UK practice and are also less uniform between centres.
Chapter 1 deals with basic blood service, laboratory and
clinical procedures, many of which differ from those practised
in the UK. For epidemiological reasons, the range of transfusion-transmitted microorganisms for which tests are done differs, testing relevant to West Nile virus and Trypanosoma cruzi
being selective in the UK. Conversely, because of the occurrence of variant Creutzfeld–Jakob disease in the UK, blood is
uniformly leucodepleted whereas the USA is ‘moving towards’
this practice. In contrast to the UK, the use of cytomegalovirus (CMV)-negative donors for blood products for neonates
is not consistent in the USA. The use of pooled platelets from
4–6 donors is discussed whereas the UK places emphasis on
reducing exposure of neonates to multiple donors so that the
great majority of platelet transfusions in neonates are of
apheresis platelets. Transfusion of maternal blood into a neonate is mentioned but the need for irradiation when blood is
from a relative is not mentioned until 15 pages later.
Chapter 2 details a practical approach to selection of
blood products and their administration including discussion
of indications and thresholds while chapter 3 deals with the
causes and management of neonatal anaemia, polycythaemia,
thrombocytopenia, neutropenia and coagulopathy, particularly vitamin K deficiency.
Chapter 4 deals with haemolytic disease of the fetus and
newborn. This term is used in an unconventional manner
ª 2017 John Wiley & Sons Ltd
British Journal of Haematology, 2017, 179, 514–515
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