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2004
Carboxylic hydrazides
Q 0493
Synthesis and Antimicrobial Activity of 2-(2,4-Dinitrophenylhydrazono)-4-oxoAcids and Their 3-Bromo Derivatives. — The title dinitrophenylhydra44- 098 butanoic
zones (III) as well as their derivatives (IV), prepared by condensation of oxobutanoic
acids (I) with dinitrophenylhydrazine (II) followed by bromination, possess antimicrobial activity. It is shown for the first time that reaction of the hydrazonooxobutanoic
acids with Ac2O proceeds with cyclocondensation to give δ-lactones (V). —
(KOZ'MINYKH, V. O.; BELYAEV, A. O.; KOZ'MINYKH, E. N.; BUKANOVA, E.
V.; ODEGOVA, T. F.; Khim.-Farm. Zh. 38 (2004) 7, 22-26; Permskii gos. pedagog.
univ., Perm', Russia; Russ.) — Mischke
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