close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2004
Etherification
O 0328
Deacylative Oxidation Strategy for the Preparation of α-Functionalized Carbonyls. — A novel protocol for α-alkoxylation and amination of carbonyl derivatives is
46- 057 developed
in a unique deacylative coupling reaction that proceeds via in situ Rh-carbene formation and subsequent insertion of a nucleophile. The smooth reaction gives
good yields starting from five- and six-membered ring lactone and lactam derivatives
using both alcohol and carbamate substrates as coupling partners. MeOH and tBuOH
lead to diminished yields. β-Dicarbonyls such as (XX) as starting materials are found
to be effective, affording α-functionalized esters. — (BRODSKY, B. H.; DU BOIS*,
J.; Org. Lett. 6 (2004) 15, 2619-2621; Dep. Chem., Stanford Univ., Stanford,
CA 94305, USA; Eng.) — Steudel
2004
Документ
Категория
Без категории
Просмотров
0
Размер файла
42 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа