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2004
Imidazole derivatives
R 0190
Synthesis and Anticonvulsant Activity of Some ω-(1H-Imidazol-1-yl)-N-phenylacand Propionamide Derivatives. — The effect of disubstitution or bulky
47- 117 etamide
monosubstitution at ortho-position of the phenyl ring in eight new (imidazolyl)phenylacetamide and propionamide derivatives in terms of anti-maximal electroshock test
activity is investigated. In general, the acetamides are more active than their propionamide counterparts. Title derivatives (V) display statistically significant activity. —
(SOYER, Z.; KILIC, F. S.; EROL, K.; PABUCCUOGLU*, V.; Farmaco 59 (2004) 8,
595-600; Dep. Pharm. Chem., Fac. Pharm., Univ. Ege, TR-35100 Bornova, Turk.;
Eng.) — H. Hoennerscheid
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