close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2004
Fused pyrimidine derivatives
R 0515
Reactions of 3,4-Dichloro-N-R-maleimides with Substituted 2-Thiouracils. —
of the title maleimides (I) with substituted uracils (II) under conditions of ther48- 138 Reaction
modynamic control affords pyrrolothiazolopyrimidinetriones (III), while reaction under milder conditions provides a mixture of regioisomers (III)/(V) in approximately
equal amounts. Similar reaction of maleimides (I) with benzo-anellated analogue of
thiouracil (VI) under mild conditions also gives isomeric pyrrolotriazoloquinazolinetriones (VII)/(VIII) in equal amounts. Derivatives (III) suffer ring opening accompanied by decarboxylation [→(IV)] on refluxing in aqueous dioxane in the presence of
triethylamine. — (VOLOVENKO, Y. M.; DUBNINA, G. G.; CHERNEGA, A. N.;
Chem. Heterocycl. Compd. (N. Y.) 40 (2004) 1, 94-100; Dep. Chem., Kiev Natl. Taras
Shevchenko Univ., Kiev 252017, Ukraine; Eng.) — H. Toeppel
Документ
Категория
Без категории
Просмотров
0
Размер файла
28 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа