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2004
Benzofuran derivatives
R 0070
Scope of Mercuric Acetate Oxidation of Chalcones and the Antibacterial Activity
Resulting Aurones. — Hg(OAc)2 provides a convenient reagent for the oxidative
49- 099 of
cyclization of 2'-hydroxychalcones like (I) or (III) resulting in stereospecific formation
of Z-aurones, e.g. (II), (IV) and (VI). Their antibacterial activity is studied against Staphylococcus aureus and Escherichia coli. The highest activity, 75% of that shown by
norfloxacin, is shown by (VI) against S. aureus. — (KHAN*, M. S. Y.; MUEED, M.
A.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 43 (2004) 8, 1794-1797;
Dep. Pharm. Chem., Hamdard Univ., New Delhi 110 062, India; Eng.) — H. Haber
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