close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2004
Alkaloids
U 0600
49- 187
Himbacine Analogues as Muscarinic Receptor Antagonists — Effects of Tether
and Heterocyclic Variations. — The synthesis and antimuscarinic activity of a number of dimethylpyrrolidinyl analogues as well as tether modified analogues of the natural product himbacine [cf. (X), (XI)] are reported. Key step of the synthetic route is
the [3+2] nitrone cycloaddition to the tricyclic alkene (IV) to attach the pyrrolidinyl
unit to the tricyclic himbacine skeleton. — (CHACKALAMANNIL*, S.; DOLLER,
D.; MCQUADE, R.; RUPERTO, V.; Bioorg. Med. Chem. Lett. 14 (2004) 15,
3967-3970; Schering-Plough Res. Inst., Kenilworth, NJ 07033, USA; Eng.) —
M. Schroeter
Документ
Категория
Без категории
Просмотров
0
Размер файла
23 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа