close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2004
Indole derivatives
R 0140
New Synthetic Method for Indole-2-carboxylate and Its Application to the Total
of Duocarmycin SA. — A sequential coupling and cyclization reaction
50- 075 Synthesis
between aryl halides (I) and methyl propiolate is developed. The formation of (IV) is
favored when the aromatic ring has electron-withdrawing groups. Excess of (II) and
Pd(PPh3)4 as the catalyst is required to provide an efficient system for the cyclization
reactions. This reaction is applied to the total synthesis of title compound (V). —
(HIROYA*, K.; MATSUMOTO, S.; SAKAMOTO, T.; Org. Lett. 6 (2004) 17,
2953-2956; Grad. Sch. Pharm. Sci., Tohoku Univ., Aoba, Sendai 980, Japan; Eng.) —
Steudel
Документ
Категория
Без категории
Просмотров
0
Размер файла
19 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа