close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2004
Indole derivatives
R 0140
Rational Design of 6-Methylsulfonylindoles as Selective Cyclooxygenase-2 Inhib— A variety of 6-methylsulfonylindoles such as (IV), (IX), (XI), and (XV) are
52- 098 itors.
synthesized and evaluated for their inhibitory activity against COX-2 and COX-1. The
3-aryloxy-, 3-arylthio- and 3-arylmethyl-2-methylindoles with 4-fluoro- or 2,4-difluorophenyl substitution, in general, display excellent potency and selectivity for inhibition of COX-2. — (CAMPBELL*, J. A.; et al.; Bioorg. Med. Chem. Lett. 14 (2004)
18, 4741-4745; Roche, Palo Alto, CA 94304, USA; Eng.) — R. Staver
2004
Документ
Категория
Без категории
Просмотров
0
Размер файла
32 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа