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2005
Antibiotics
U 1200
02- 219
Synthesis of Novel 26-Substituted Milbemycin A4 Derivatives and Their Acaricidal Activities. — Novel 26-substituted milbemycin A4 derivatives are prepared and
their acaricidal activities are determined. Compounds such as (Ia)—(Ic) show good
activity against the two-spotted spider mite. The dependence of the activity on the
nature of the substituent R is discussed. — (TSUKIYAMA*, T.; KAJINO, H.;
TSUKAMOTO, Y.; NAKAGAWA, H.; YANAI, T.; SATO, K.; YOKOI, S.;
ICHINOSE, R.; TANAKA, K.; J. Antibiot. 57 (2004) 7, 446-455; Agrosci. Res. Lab.,
Sankyo Co. Ltd., Yasu, Shiga 520-23, Japan; Eng.) — M. Bohle
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