close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Enantioselective syntheses
O 0031
α-Hydroxy Ketones in High Enantiomeric Purity from Asymmetric Oxidation
of Enol Phosphates with (salen) Manganese(III) Complex. — The easily available
03- 035 (E)-enol
phosphates (I), (III) or (V) undergo stereoselective epoxidation in the presence
of Jacobsen's complex. After ring opening with TFA, the α-hydroxy ketones (II), (IV)
or (VI) are obtained with up to 95% e.e. The absolute configuration is controlled by the
steric bulk and electronic factors of the phosphate group. The low yield of (VI) is
caused by a competing aromatization reaction. — (KRAWCZYK*, E.;
KOPROWSKI, M.; SKOWRONSKA, A.; LUCZAK, J.; Tetrahedron: Asymmetry 15
(2004) 17, 2599-2602; Cent. Mol. Macromol. Stud., Pol. Acad. Sci., PL-90-363 Lodz,
Pol.; Eng.) — Kieslich
Документ
Категория
Без категории
Просмотров
0
Размер файла
154 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа