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2005
Fused pyrimidine derivatives
R 0515
Activated Nitriles in Heterocyclic Chemistry: Facile Synthesis and Antimicrobial
of Some Pyrimidine, Pyrazolopyrimidine and Pyrazolotriazine Deriva05- 138 Activity
tives Containing Sulfonamido Moiety. — A variety of novel title pyrimidines and
pyrazolotriazines containing a sulfonamido moiety are synthesized using readily available hydrazones (III) as starting compounds. Compounds (IIc) and (Va) show antimicrobial activity similar to the standard streptomycin, while most of the remaining compounds show moderate antimicrobial activity. — (AMMAR, Y. A.; SALEH, N. M.;
MICKY, J. A.; ABBAS, H. A. S.; EL-GABY*, M. S. A.; Indian J. Chem., Sect. B:
Org. Chem. Incl. Med. Chem. 43 (2004) 10, 2203-2211; Dep. Chem., Fac. Sci.,
Al-Azhar Univ., Assiut 71511, Egypt; Eng.) — A. Forchert
2005
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