close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Enantioselective syntheses
O 0031
Copper-Catalyzed Enantioselective Conjugate Addition of Grignard Reagents to
Enones. — Under optimized conditions (copper salt, ferrocenyl ligand, and
06- 041 Acyclic
solvent), Grignard reagents including sterically hindered alkyl-substituted and aryl
derivatives are efficiently added to a variety of achiral acyclic (E)- and (Z)-enones.
Optically active β-substituted acyclic ketones are formed with high yields and enantioselectivites. Opposite enantiomers for a particular ketone can be obtained by judicious
selection of complementary enones and Grignard reagents without changing the configuration of the chiral diphosphine ligand. — (LOPEZ, F.; HARUTYUNYAN, S. R.;
MINNAARD, A. J.; FERINGA*, B. L.; J. Am. Chem. Soc. 126 (2004) 40,
12784-12785; Dep. Org. Chem., Univ. Groningen, NL-9747 AG Groningen, Neth.;
Eng.) — Klein
Документ
Категория
Без категории
Просмотров
0
Размер файла
42 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа