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2005
Imidazole derivatives
R 0190
Synthesis and Antituberculosis Activity of N-Aryl-C-nitroazoles. —
derivatives of 4-nitroimidazoles (III) and (VIII), 4-nitropyrazole (VI), and
11- 139 N-Aryl
3-nitro-1,2,4-triazole (X) are synthesized either by degenerated ring transformation
reaction of 1,4-dinitroimidazoles (I) with 4-substituted anilines (II) or by condensation
of fluoronitrobenzenes (V) with DBU salts of C-nitro-1H-azoles (IV), (VII), and (IX).
All products are tested for their anti-tuberculosis activity. — (WALCZAK, K.;
GONDELA, A.; SUWINSKI*, J.; Eur. J. Med. Chem. 39 (2004) 10, 849-853; Dep.
Org. Bioorg. Chem. Biotechnol., Silesian Univ. Technol., PL-44-100 Gliwice, Pol.;
Eng.) — H. Haber
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