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2005
Pyridine derivatives
R 0380
Conversion from Arenes Having a Benzene Ring to those Having a Picolinic Acid
Simple Growing Cell Reactions Using Escherichia coli that Expressed the Six
11- 153 by
Bacterial Genes Involved in Biphenyl Catabolism. — A recombinant E. coli JM109
strain, expressing six genes encoding biphenyl dioxygenase, dihydrodiol dehydrogenase, and catechol 2,3-dioxygenase, is employed to convert the phenyl group of the substrates into a 6-carboxypyridin-2-yl moiety. It is assumed that the nitrogen in the pyridine ring is very likely derived from the ammonium chloride present in the M9 medium.
— (SHINDO*, K.; OSAWA, A.; NAKAMURA, R.; KAGIYAMA, Y.; SAKUDA, S.;
SHIZURI, Y.; FURUKAWA, K.; MISAWA, N.; J. Am. Chem. Soc. 126 (2004) 46,
15042-15043; Dep. Food Nutr., Japan Women's Univ., Bunkyo, Tokyo 112, Japan;
Eng.) — Klein
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