close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Indan derivatives
Q 1050
Organocatalytic Asymmetric Hydroxylation of β-Keto Esters: Metal-Free Syntheof Optically Active anti-Diols. — Application of cumene hydroperoxide as oxy12- 103 sis
gen source and dihydroquinine as organocatalyst in the α-hydroxylation of β-ketoesters
(I) and (IV) leads to high yields and up to 80% e.e. of hydroxylated products (II) and
(V), except for the tert-butyl ester (Id). The optically active products undergo diastereoselective reduction in the presence of BH3·4-ethylmorpholine as reducing reagent to
give almost exclusively anti-diols (III) and (VI). — (ACOCELLA, M. R.;
MANCHENO, O. G.; BELLA, M.; JOERGENSEN*, K. A.; J. Org. Chem. 69 (2004)
23, 8165-8167; Dep. Chem., Univ. Aarhus, DK-8000 Aarhus, Den.; Eng.) — Klein
Документ
Категория
Без категории
Просмотров
0
Размер файла
26 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа