close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Triazole derivatives
R 0280
Synthesis of Some 3-(Arylalkylthio)-4-alkyl/aryl-5-(4-aminophenyl)-4H-1,2,4-triDerivatives and Their Anticonvulsant Activity. — The synthesis of the title
12- 136 azole
triazoles (VI) is aimed at investigating antimicrobial and antimycobacterial properties
in addition to their anticonvulsant activities. The primary amino group in (VI) is
masked to observe the contribution of this function to pharmacological activity. Protective activities in the maximal electroshock (MES) test as well as in the subcutaneous
pentylenetetrazole (sc PTZ) test are shown by triazoles (VIa) and (VIb). The novel triazoles are devoid of antibacterial and antimycobacterial activity. Triazoles (VIc) and
(VIII) display marginal activity against M. tuberculosis H37. —
(KUECUEKGUEZEL, I.; KUECUEKGUEZEL, G. S.; ROLLAS, S.;
OETUEK-SANIS, G.; OEZDEMIR, O.; BAYRAK, I.; ALTUG, T.; STABLES, J. P.;
Farmaco 59 (2004) 11, 893-901; Dep. Pharm. Chem., Fac. Pharm., Marmara Univ.,
Haydarpasa, TR-81010 Istanbul, Turk.; Eng.) — H. Hoennerscheid
Документ
Категория
Без категории
Просмотров
0
Размер файла
22 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа