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2005
Benzimidazole derivatives
R 0200
Synthesis of Novel 2-[2-(Substituted amino)phenethyl]-1H-benzimidazoles;
and 1,2,3,4-Tetrahydropyrimido[1,6-a]-benzimidazoles as Potential
13- 132 3,4-DihydroAntiulcer Agents. — The synthesis of a series of novel substituted benzimidazoles
with potential antiulcer effects is carried out. Products (V), (IX), and (XVI) are tested
for their gastric antisecretory activity in vivo: their activity is comparable to that of
omeprazole. — (SHAFIK, R. M.; EL-DIN, S. A. S.; ESHBA, N. H.; EL-HAWASH*,
S. A. M.; DESHEESH, M. A.; ABDEL-ATY, A. S.; ASHOUR, H. M.; Pharmazie 59
(2004) 12, 899-905; Dep. Pharm. Chem., Fac. Pharm., Alexandria Univ., Alexandria
21521, Egypt; Eng.) — R. Staver
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