close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Quinoline derivatives
R 0410
Inhibition of the Arachidonic Acid Cascade by Aza-2-aryl-1,4-naphthoquinone
— Searching for novel potent 5-lipoxygenase inhibitors, a variety of
14- 155 Derivatives.
quinone derivatives are prepared. In the demethylation of quinone (XV), concomitant
loss of one tBu-group is observed. Compounds (VIII), (XIII), (XV), and (XVI) demonstrate highly selective and potent inhibition of 5-lipoxygenase. Derivatives (VII) and
(XII) are dual 5-lipoxygenase and COX-1 inhibitors. — (RICHWIEN, A.; WURM*,
G.; Pharmazie 59 (2004) 12, 906-912; Inst. Pharm., FU Berlin, D-14195 Berlin,
Germany; Ger., Abstr. Eng.) — R. Staver
Документ
Категория
Без категории
Просмотров
0
Размер файла
29 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа