close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Hormones
U 1000
15- 207
Chemical Transformations of 9,11-Ethano-13,15-isoxazolinoprostanoids. — The
heterocyclic ring of isoxazolinoprostanoid derivatives is cleaved under hydrogenolysis
conditions to give β-hydroxyketones like (II) or γ-amino alcohols (VII). In the case of
prostanoid (VIII), spontaneous dehydration occurs under hydrogenolysis conditions in
addition to the ring cleavage to afford unsaturated ketone (IX). Analogous
ketones are derived from treatment of alcohols (II) with MesCl/Et3N. Nucleophilic
addition of thiols to ketones (III) provides thiaprostanoids (V) and (VI). —
(BONDAR', N. F.; ISAENYA, L. P.; SKUPSKAYA, R. V.; LAKHVICH, F. A.; Russ.
J. Org. Chem. 39 (2003) 8, 1095-1103; Inst. Bioorg. Chem., Belarus Acad. Sci.,
Minsk 220141, Belarus; Eng.) — Klein
Документ
Категория
Без категории
Просмотров
0
Размер файла
35 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа