close

Вход

Забыли?

вход по аккаунту

?

код для вставки
200517.fm Page 95 Friday, March 18, 2005 2:52 PM
2005
Carboxylic acid esters
Q 0530
Asymmetric Conjugate Reduction of α,β-Unsaturated Esters with Chiral RhodiCatalysts. — By use of diethoxy(methyl)silane as hydro17- 091 um(bisoxazolinylphenyl)
gen donor and the rhodium acetate complex as catalyst, a variety of (E)-esters (I) are
reduced with high enantioselectivities. It is noteworthy that the non-conjugated alkene
group in ester (If) remains intact. In the case of (Z)-ester (IIIa), a rapid isomerization
to the (E)-ester (Ia) is unexpectedly observed after a short reaction time. At longer
reaction time, reduction of the (E)-ester leads to a decreased enantioselectivity of the
(S)-product. No isomerization occurs in the case of (Z)-ester (IIIe). — (TSUCHIYA,
Y.; KANAZAWA, Y.; SHIOMI, T.; KOBAYASHI, K.; NISHIYAMA*, H.; Synlett
2004, 14, 2493-2496; Dep. Appl. Chem., Fac. Eng., Nagoya Univ., Chikusa,
Nagoya 464, Japan; Eng.) — Klein
Документ
Категория
Без категории
Просмотров
0
Размер файла
31 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа