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200517.fm Page 128 Friday, March 18, 2005 2:52 PM
2005
Pyrrole derivatives
R 0120
Synthesis of Arylidine Derivatives of 1-Aryl-3H-pyrrol-2-ones. — A convenient
for the synthesis of the title pyrrole derivatives (IV) based on the aminolysis of
17- 116 method
corresponding furan derivatives (I) followed by azacyclization of the obtained
4-oxoamides (III) is developed. Synthesis of compounds (IV) by condensation of pyrrolones (V) with aromatic aldehydes takes place slowly and provides significantly lower yields. — (EGOROVA, A. Y.; NESTEROVA, V. V.; Chem. Heterocycl. Compd.
(N. Y.) 40 (2004) 8, 1002-1006; Chernyshevskii Saratov State Univ., Saratov 410026,
Russia; Eng.) — H. Toeppel
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