close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Enantioselective syntheses
O 0031
Lewis Base Activation of Lewis Acids: Vinylogous Aldol Additions of Silyl Dienol
to Aldehydes. — The addition of aldehydes (II) towards silyl enol ethers (I)
18- 026 Ethers
derived from simple α,β-unsaturated ketones in the presence of the chiral bis(phosphoramide) BPPA represents the first example of catalytic enantioselective vinylogous
aldol reaction. The reaction proceeds with exclusive γ-regioselectivity and with high to
excellent diastereo- and enantioselectivity. Aromatic, hetaromatic, olefinic and propargylic aldehydes are suitable substrates while no reaction occurs with aliphatic aldehydes. — (DENMARK*, S. E.; HEEMSTRA, J. R. J.; Synlett 2004, 13, 2411-2416;
Dep. Chem., Univ. Ill., Urbana, IL 61801, USA; Eng.) — Mischke
Документ
Категория
Без категории
Просмотров
0
Размер файла
28 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа